Original language | English (US) |
---|---|
Pages (from-to) | 4514-4517 |
Number of pages | 4 |
Journal | Blood Advances |
Volume | 7 |
Issue number | 16 |
DOIs | |
State | Published - Aug 16 2023 |
Externally published | Yes |
ASJC Scopus subject areas
- Hematology
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In: Blood Advances, Vol. 7, No. 16, 16.08.2023, p. 4514-4517.
Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - Loss-of-function lesions impact B-cell development and fitness but are insufficient to drive CLL in mouse models
AU - ten Hacken, Elisa
AU - Yin, Shanye
AU - Redd, Robert
AU - Sánchez, María Hernández
AU - Clement, Kendell
AU - Hoffmann, Gabriela Brunsting
AU - Regis, Fara F.
AU - Witten, Elizabeth
AU - Li, Shuqiang
AU - Neuberg, Donna
AU - Pinello, Luca
AU - Livak, Kenneth J.
AU - Wu, Catherine J.
N1 - Funding Information: Conflict-of-interest disclosure: C.J.W. is an equity holder of BioNTech Inc. and receives research funding from Pharmacyclics. L.P. has financial interests in Edilytics Inc. K.C. is an employee, shareholder, and officer of Edilytics Inc. The interests of L.P. and K.C. were reviewed and are managed by Massachusetts General Hospital and Partners HealthCare in accordance with their conflict-of-interest policies. The remaining authors declare no competing financial interests. Funding Information: Acknowledgments: The authors thank members of the Wu lab for the valuable discussions. The authors are also grateful for excellent technical assistance from the Dana-Farber Cancer Institute Animal Research Facility and the Dana-Faber Cancer Institute Flow Cytometry Core. This study was supported by grants from the National Institutes of Health/National Cancer Institute (P01 CA206978 and R01CA216273). E.t.H. is a scholar of the American Society of Hematology. S.Y. is supported by a research fellowship from the Lauri Strauss Leukemia Foundation and National Cancer Institute (R21 CA267527-01). M.H.S. has been supported by a Sara Borrell postdoctoral contract (CD19/00222) from the Instituto de Salud Carlos III (ISCIII), cofounded by Fondo Social Europeo “El Fondo Social Europeo invierte en tu futuro.” K.C. is supported by National Human Genome Research Institute Career Development Award K99HG011658. S.L. is supported by the National Cancer Institute Research Specialist Award (R50CA251956). L.P. is partially supported by National Human Genome Research Institute Genomic Innovator Award R35HG010717.
PY - 2023/8/16
Y1 - 2023/8/16
UR - http://www.scopus.com/inward/record.url?scp=85170075281&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85170075281&partnerID=8YFLogxK
U2 - 10.1182/bloodadvances.2022009135
DO - 10.1182/bloodadvances.2022009135
M3 - Article
C2 - 36477552
AN - SCOPUS:85170075281
SN - 2473-9529
VL - 7
SP - 4514
EP - 4517
JO - Blood Advances
JF - Blood Advances
IS - 16
ER -