Loss of cyclophilin D prolyl isomerase activity desensitizes mitochondrial permeability transition pore opening in isolated cardiac mitochondria, but does not protect in myocardial ischemia-reperfusion injury

Kevin M. Casin; Moises Bustamante; Georgios Amanakis; Junhui Sun; Chengyu Liu; Richard N. Kitsis; Elizabeth Murphy

doi:10.1016/j.yjmcc.2023.09.003

Loss of cyclophilin D prolyl isomerase activity desensitizes mitochondrial permeability transition pore opening in isolated cardiac mitochondria, but does not protect in myocardial ischemia-reperfusion injury

Kevin M. Casin, Moises Bustamante, Georgios Amanakis, Junhui Sun, Chengyu Liu, Richard N. Kitsis, Elizabeth Murphy

Medicine

Research output: Contribution to journal › Letter › peer-review

Original language	English (US)
Pages (from-to)	67-69
Number of pages	3
Journal	Journal of Molecular and Cellular Cardiology
Volume	183
DOIs	https://doi.org/10.1016/j.yjmcc.2023.09.003
State	Published - Oct 2023

Keywords

Cyclophilin D
Cyclosporine A
Ischemia-reperfusion injury
Mitochondria permeability transition pore
Prolyl isomerase

ASJC Scopus subject areas

Molecular Biology
Cardiology and Cardiovascular Medicine

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10.1016/j.yjmcc.2023.09.003

Cite this

Casin, K. M., Bustamante, M., Amanakis, G., Sun, J., Liu, C., Kitsis, R. N., & Murphy, E. (2023). Loss of cyclophilin D prolyl isomerase activity desensitizes mitochondrial permeability transition pore opening in isolated cardiac mitochondria, but does not protect in myocardial ischemia-reperfusion injury. Journal of Molecular and Cellular Cardiology, 183, 67-69. https://doi.org/10.1016/j.yjmcc.2023.09.003

Loss of cyclophilin D prolyl isomerase activity desensitizes mitochondrial permeability transition pore opening in isolated cardiac mitochondria, but does not protect in myocardial ischemia-reperfusion injury. / Casin, Kevin M.; Bustamante, Moises; Amanakis, Georgios et al.
In: Journal of Molecular and Cellular Cardiology, Vol. 183, 10.2023, p. 67-69.

Research output: Contribution to journal › Letter › peer-review

Casin, KM, Bustamante, M, Amanakis, G, Sun, J, Liu, C, Kitsis, RN & Murphy, E 2023, 'Loss of cyclophilin D prolyl isomerase activity desensitizes mitochondrial permeability transition pore opening in isolated cardiac mitochondria, but does not protect in myocardial ischemia-reperfusion injury', Journal of Molecular and Cellular Cardiology, vol. 183, pp. 67-69. https://doi.org/10.1016/j.yjmcc.2023.09.003

Casin KM, Bustamante M, Amanakis G, Sun J, Liu C, Kitsis RN et al. Loss of cyclophilin D prolyl isomerase activity desensitizes mitochondrial permeability transition pore opening in isolated cardiac mitochondria, but does not protect in myocardial ischemia-reperfusion injury. Journal of Molecular and Cellular Cardiology. 2023 Oct;183:67-69. doi: 10.1016/j.yjmcc.2023.09.003

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title = "Loss of cyclophilin D prolyl isomerase activity desensitizes mitochondrial permeability transition pore opening in isolated cardiac mitochondria, but does not protect in myocardial ischemia-reperfusion injury",

keywords = "Cyclophilin D, Cyclosporine A, Ischemia-reperfusion injury, Mitochondria permeability transition pore, Prolyl isomerase",

author = "Casin, {Kevin M.} and Moises Bustamante and Georgios Amanakis and Junhui Sun and Chengyu Liu and Kitsis, {Richard N.} and Elizabeth Murphy",

note = "Funding Information: Our research was funded by the NHLBI-NIH Intramural Research Program ( ZO1-HL002066 ) and Leducq Foundation grant ( 16CVD04 ).",

year = "2023",

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doi = "10.1016/j.yjmcc.2023.09.003",

language = "English (US)",

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pages = "67--69",

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T1 - Loss of cyclophilin D prolyl isomerase activity desensitizes mitochondrial permeability transition pore opening in isolated cardiac mitochondria, but does not protect in myocardial ischemia-reperfusion injury

AU - Casin, Kevin M.

AU - Bustamante, Moises

AU - Amanakis, Georgios

AU - Sun, Junhui

AU - Liu, Chengyu

AU - Kitsis, Richard N.

AU - Murphy, Elizabeth

N1 - Funding Information: Our research was funded by the NHLBI-NIH Intramural Research Program ( ZO1-HL002066 ) and Leducq Foundation grant ( 16CVD04 ).

PY - 2023/10

Y1 - 2023/10

KW - Cyclophilin D

KW - Cyclosporine A

KW - Ischemia-reperfusion injury

KW - Mitochondria permeability transition pore

KW - Prolyl isomerase

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U2 - 10.1016/j.yjmcc.2023.09.003

DO - 10.1016/j.yjmcc.2023.09.003

M3 - Letter

C2 - 37696137

AN - SCOPUS:85170218668

SN - 0022-2828

VL - 183

SP - 67

EP - 69

JO - Journal of Molecular and Cellular Cardiology

JF - Journal of Molecular and Cellular Cardiology

ER -

Loss of cyclophilin D prolyl isomerase activity desensitizes mitochondrial permeability transition pore opening in isolated cardiac mitochondria, but does not protect in myocardial ischemia-reperfusion injury

Keywords

ASJC Scopus subject areas

Access to Document

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