Literature update in hospital medicine

William Southern, Bradley A. Sharpe, Romsai Tony Boonyasai

Research output: Contribution to journalReview articlepeer-review


Perioperative statins reduce perioperative myocardial infarctions, atrial fibrillation, and length of stay. Statins do not increase the risk of intracranial hemorrhage. New oral anticoagulants are superior to warfarin in preventing stroke in patients with atrial fibrillation, and may have a better safety profile. In patients who have an acute gastrointestinal bleed while on warfarin, restarting warfarin after a week may lead to fewer thromboses and lower mortality without increasing the bleeding risk. Patients with an exacerbation of chronic obstructive pulmonary disease should receive antibiotics, bronchodilators, and steroids. A 7-day course of oral ciprofloxacin should be considered for acute, uncomplicated pyelonephritis.

Original languageEnglish (US)
Pages (from-to)e293-e303
JournalHospital Medicine Clinics
Issue number2
StatePublished - Apr 2014


  • Antibiotic usage
  • Anticoagulation
  • Clostridium difficile
  • Evidence-based medicine
  • Perioperative medicine

ASJC Scopus subject areas

  • General Medicine


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