Abstract
Individuals with amnestic mild cognitive impairment (aMCI) show deficits on traditional episodic memory tasks and reductions in speed of performance on reaction time tasks. We present results on a novel task, the Cued-Recall Retrieval Speed Task (CRRST), designed to simultaneously measure level and speed of retrieval. A total of 390 older adults (mean age, 80.2 years), learned 16 words based on corresponding categorical cues. In the retrieval phase, we measured accuracy (% correct) and retrieval speed/reaction time (RT; time from cue presentation to voice onset of a correct response) across 6 trials. Compared to healthy elderly adults (HEA, n = 303), those with aMCI (n = 87) exhibited poorer performance in retrieval speed (difference = -0.13; p <.0001) and accuracy on the first trial (difference = -0.19; p <.0001), and their rate of improvement in retrieval speed was slower over subsequent trials. Those with aMCI also had greater within-person variability in processing speed (variance ratio = 1.22; p =.0098) and greater between-person variability in accuracy (variance ratio = 2.08; p =.0001) relative to HEA. Results are discussed in relation to the possibility that computer-based measures of cued-learning and processing speed variability may facilitate early detection of dementia in at-risk older adults.
Original language | English (US) |
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Pages (from-to) | 260-268 |
Number of pages | 9 |
Journal | Journal of the International Neuropsychological Society |
Volume | 18 |
Issue number | 2 |
DOIs | |
State | Published - Mar 2012 |
Keywords
- Amnestic mild cognitive impairment
- Cued-recall task
- Intraindividual variability
- Neuropsychological assessment
- Retrieval speed
- Variability
ASJC Scopus subject areas
- General Neuroscience
- Clinical Psychology
- Clinical Neurology
- Psychiatry and Mental health