Leptospirosis in travelers

Reinout Van Crevel, Peter Speelman, Claudia Gravekamp, Wiepko J. Terpstra

Research output: Contribution to journalArticlepeer-review

96 Scopus citations


Between 1987 and 1991 leptospirosis in 32 Dutch travelers was diagnosed. Infections were acquired predominantly in Thailand and other Southeast Asian countries. Contact with surface waters could be confirmed in all but one case. Fever, headache, and myalgia were the most common complaints. Signs included conjunctival injection and lymphadenopathy in 11 patients each, jaundice in 8, and nuchal rigidity in 3; renal function was impaired in 8. Leptospires were isolated from the blood or urine of nine patients. Thirty-one patients developed an antibody response. Classification of strains identified a variety of serogroups. Although only 14 patients received adequate treatment, all patients recovered completely. Since the number of patients with imported leptospirosis is increasing and the signs and symptoms of the disease are not specific, leptospirosis should be included in the differential diagnosis when a traveler returns from the Tropics with fever.

Original languageEnglish (US)
Pages (from-to)132-134
Number of pages3
JournalClinical Infectious Diseases
Issue number1
StatePublished - Jul 1994
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases


Dive into the research topics of 'Leptospirosis in travelers'. Together they form a unique fingerprint.

Cite this