Leadless Pacemakers: State of the Art and Future Perspectives

Domenico G. Della Rocca, Carola Gianni, Luigi Di Biase, Andrea Natale, Amin Al-Ahmad

Research output: Contribution to journalReview articlepeer-review

15 Scopus citations


Leadless pacemaker therapy is a new technology that aims at avoiding lead- and pocket-related complications of conventional transvenous and epicardial pacing. To date, 2 self-contained leadless pacemakers for right ventricular pacing have been clinically available: the Nanostim Leadless Pacemaker System and the Micra Transcatheter Pacing System. Additionally, a new multicomponent leadless pacemaker for endocardial left ventricular pacing has been proposed as an alternative choice for cardiac resynchronization therapy. In this review, we describe the state of the art of leadless pacing and compare the currently available devices with traditional transvenous leadless pacemakers.

Original languageEnglish (US)
Pages (from-to)17-29
Number of pages13
JournalCardiac Electrophysiology Clinics
Issue number1
StatePublished - Mar 2018


  • Bradyarrhythmias
  • Cardiac arrhythmias
  • Cardiac pacing
  • Cardiac resynchronization therapy
  • Leadless pacemaker
  • Transvenous leads
  • Transvenous pacemaker

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)


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