TY - JOUR
T1 - Latest advances in aging research and drug discovery
AU - Bakula, Daniela
AU - Ablasser, Andrea
AU - Aguzzi, Adriano
AU - Antebi, Adam
AU - Barzilai, Nir
AU - Bittner, Martin Immanuel
AU - Jensen, Martin Borch
AU - Calkhoven, Cornelis F.
AU - Chen, Danica
AU - de Grey, Aubrey D.N.J.
AU - Feige, Jerome N.
AU - Georgievskaya, Anastasia
AU - Gladyshev, Vadim N.
AU - Golato, Tyler
AU - Gudkov, Andrei V.
AU - Hoppe, Thorsten
AU - Kaeberlein, Matt
AU - Katajisto, Pekka
AU - Kennedy, Brian K.
AU - Lal, Unmesh
AU - Martin-Villalba, Ana
AU - Moskalev, Alexey A.
AU - Ozerov, Ivan
AU - Petr, Michael A.
AU - Reason,
AU - Rubinsztein, David C.
AU - Tyshkovskiy, Alexander
AU - Vanhaelen, Quentin
AU - Zhavoronkov, Alex
AU - Scheibye-Knudsen, Morten
N1 - Funding Information:
DB is supported by the German Research Foundation (Forschungsstipendium; BA 6276/1-1) and the Lundbeckfonden (#R303-2018-3159). DC is funded by the NIH (R01AG 063389, R01AG063404, R01DK117481, R01DK101885) and the NIFA. VNG is supported by NIH grants. AT is supported by the Russian Federation grant 14. W03.31.0012. TH is supported by the Deutsche Forschungsgemeinschaft (DFG) (CECAD) and the European Research Council (consolidator grant 616499). DCR is grateful for funding from the UK Dementia Research Institute (funded by the MRC, Alzheimer's Research UK and the Alzheimer's Society) (DCR), an anonymous donation to the Cambridge Centre for Parkinson-Plus, The Rosetrees Trust, The Tau Consortium and The Roger de Spoelberch Foundation (DCR). MSK is funded by the Nordea Foundation (#02-2017-1749), the Novo Nordisk Foundation (#NNF17OC0027812), the Danish Cancer Society (#R167-A11015_001), the Independent Research Fund Denmark (#7016-00230B), the Neye Foundation and Insilico Medicine.
Publisher Copyright:
© Bakula et al.
PY - 2019
Y1 - 2019
N2 - An increasing aging population poses a significant challenge to societies worldwide. A better understanding of the molecular, cellular, organ, tissue, physiological, psychological, and even sociological changes that occur with aging is needed in order to treat age-associated diseases. The field of aging research is rapidly expanding with multiple advances transpiring in many previously disconnected areas. Several major pharmaceutical, biotechnology, and consumer companies made aging research a priority and are building internal expertise, integrating aging research into traditional business models and exploring new go-to-market strategies. Many of these efforts are spearheaded by the latest advances in artificial intelligence, namely deep learning, including generative and reinforcement learning. To facilitate these trends, the Center for Healthy Aging at the University of Copenhagen and Insilico Medicine are building a community of Key Opinion Leaders (KOLs) in these areas and launched the annual conference series titled "Aging Research and Drug Discovery (ARDD)" held in the capital of the pharmaceutical industry, Basel, Switzerland (www.agingpharma.org). This ARDD collection contains summaries from the 6th annual meeting that explored aging mechanisms and new interventions in age-associated diseases. The 7th annual ARDD exhibition will transpire 2nd-4th of September, 2020, in Basel.
AB - An increasing aging population poses a significant challenge to societies worldwide. A better understanding of the molecular, cellular, organ, tissue, physiological, psychological, and even sociological changes that occur with aging is needed in order to treat age-associated diseases. The field of aging research is rapidly expanding with multiple advances transpiring in many previously disconnected areas. Several major pharmaceutical, biotechnology, and consumer companies made aging research a priority and are building internal expertise, integrating aging research into traditional business models and exploring new go-to-market strategies. Many of these efforts are spearheaded by the latest advances in artificial intelligence, namely deep learning, including generative and reinforcement learning. To facilitate these trends, the Center for Healthy Aging at the University of Copenhagen and Insilico Medicine are building a community of Key Opinion Leaders (KOLs) in these areas and launched the annual conference series titled "Aging Research and Drug Discovery (ARDD)" held in the capital of the pharmaceutical industry, Basel, Switzerland (www.agingpharma.org). This ARDD collection contains summaries from the 6th annual meeting that explored aging mechanisms and new interventions in age-associated diseases. The 7th annual ARDD exhibition will transpire 2nd-4th of September, 2020, in Basel.
KW - Aging
KW - Artificial intelligence
KW - Drug discovery
UR - http://www.scopus.com/inward/record.url?scp=85076017831&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85076017831&partnerID=8YFLogxK
U2 - 10.18632/aging.102487
DO - 10.18632/aging.102487
M3 - Article
C2 - 31770722
AN - SCOPUS:85076017831
SN - 1945-4589
VL - 11
SP - 9971
EP - 9981
JO - Aging
JF - Aging
IS - 22
ER -