Late motor involvement in cases presenting as “chronic sensory demyelinating polyneuropathy”

Alan R. Berger, Steven Herskovitz, Jerry Kaplan

Research output: Contribution to journalArticlepeer-review

56 Scopus citations


Chronic inflammatory demyelinating polyneuropathy (CIDP) is usually characterized by prominent motor deficits. A pure sensory presentation, labeled chronic sensory demyelinating neuropathy (CSDN), has been reported, but it is unclear if this neuropathy is a distinct clinical and immunologic entity or merely the sensory presentation of the more usual sensorimotor CIDP. We describe 5 patients with what initially appeared to be CSDN; 3 subsequently developed substantial weakness coincident with the electrophysiologic appearance of multifocal motor conduction block. These cases indicate that, in some cases, CSDN may be a transitional clinical stage of CIDP in which the more usual sensorimotor deficits develop later. Immune‐based therapy, including intravenous immunoglobulin, was found to be effective in both the pure sensory and sensorimotor types. © 1995 John Wiley & Sons, Inc.

Original languageEnglish (US)
Pages (from-to)440-444
Number of pages5
JournalMuscle & Nerve
Issue number4
StatePublished - Apr 1995

ASJC Scopus subject areas

  • Physiology
  • Clinical Neurology
  • Cellular and Molecular Neuroscience
  • Physiology (medical)


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