Isolated central nervous system granulomatosis resembling sarcoidosis

S. C. Lee; J. Spencer; J. Rumberg; D. W. Dickson

doi:10.1007/BF00314381

Isolated central nervous system granulomatosis resembling sarcoidosis

S. C. Lee, J. Spencer, J. Rumberg, D. W. Dickson

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Isolated central nervous system (CNS) granulomatosis resembling sarcoidosis occurred in a 30-year-old woman who had amenorrhea, ataxia, and obstructive hydrocephalus, and a 9-year course of progressive neurological deterioration with recurrent bouts of diabetes insipidus. Lamellar and nodular meningeal hyalinosis resembling amyloid was noted on an initial brain biopsy. At autopsy, the brain had a non-necrotizing granulomatous meningitis and ventriculitis, most prominent at the base of the brain, including the third ventricle and the hypothalamus, but there were no systemic granulomas.

Original language	English (US)
Pages (from-to)	356-358
Number of pages	3
Journal	Journal of Neurology
Volume	236
Issue number	6
DOIs	https://doi.org/10.1007/BF00314381
State	Published - Sep 1989
Externally published	Yes

Keywords

Amyloid
Isolated
Neurosarcoidosis
Pulmonary hyalinizing granuloma

ASJC Scopus subject areas

Neurology
Clinical Neurology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/BF00314381

Cite this

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title = "Isolated central nervous system granulomatosis resembling sarcoidosis",

abstract = "Isolated central nervous system (CNS) granulomatosis resembling sarcoidosis occurred in a 30-year-old woman who had amenorrhea, ataxia, and obstructive hydrocephalus, and a 9-year course of progressive neurological deterioration with recurrent bouts of diabetes insipidus. Lamellar and nodular meningeal hyalinosis resembling amyloid was noted on an initial brain biopsy. At autopsy, the brain had a non-necrotizing granulomatous meningitis and ventriculitis, most prominent at the base of the brain, including the third ventricle and the hypothalamus, but there were no systemic granulomas.",

keywords = "Amyloid, Isolated, Neurosarcoidosis, Pulmonary hyalinizing granuloma",

author = "Lee, {S. C.} and J. Spencer and J. Rumberg and Dickson, {D. W.}",

year = "1989",

month = sep,

doi = "10.1007/BF00314381",

language = "English (US)",

volume = "236",

pages = "356--358",

journal = "Journal of Neurology",

issn = "0340-5354",

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TY - JOUR

T1 - Isolated central nervous system granulomatosis resembling sarcoidosis

AU - Lee, S. C.

AU - Spencer, J.

AU - Rumberg, J.

AU - Dickson, D. W.

PY - 1989/9

Y1 - 1989/9

N2 - Isolated central nervous system (CNS) granulomatosis resembling sarcoidosis occurred in a 30-year-old woman who had amenorrhea, ataxia, and obstructive hydrocephalus, and a 9-year course of progressive neurological deterioration with recurrent bouts of diabetes insipidus. Lamellar and nodular meningeal hyalinosis resembling amyloid was noted on an initial brain biopsy. At autopsy, the brain had a non-necrotizing granulomatous meningitis and ventriculitis, most prominent at the base of the brain, including the third ventricle and the hypothalamus, but there were no systemic granulomas.

AB - Isolated central nervous system (CNS) granulomatosis resembling sarcoidosis occurred in a 30-year-old woman who had amenorrhea, ataxia, and obstructive hydrocephalus, and a 9-year course of progressive neurological deterioration with recurrent bouts of diabetes insipidus. Lamellar and nodular meningeal hyalinosis resembling amyloid was noted on an initial brain biopsy. At autopsy, the brain had a non-necrotizing granulomatous meningitis and ventriculitis, most prominent at the base of the brain, including the third ventricle and the hypothalamus, but there were no systemic granulomas.

KW - Amyloid

KW - Isolated

KW - Neurosarcoidosis

KW - Pulmonary hyalinizing granuloma

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JO - Journal of Neurology

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ER -

Isolated central nervous system granulomatosis resembling sarcoidosis

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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