Invited review: Peripheral neuropathy in Sjogren' syndrome

Jerry G. Kaplan, Richard Rosenberg, Elizabeth Reinitz, Shalom Buchbinder, Herbert H. Schaumburg

Research output: Contribution to journalArticlepeer-review

94 Scopus citations


Our experience and review of the literature reveal that Sjogren' syndrome (SS) is an important, poorly recognized cause of peripheral neuropathy. Several forms of peripheral nerve dysfunction occur in SS including trigeminal sensory neuropathy, mononeuropathy multiplex, distal sensory neuropathy, distal sensorimotor peripheral neuropathy and a pure sensory neuronopathy syndrome. Rarely, chronic relapsing inflammatory polyneuropathy and multiple cranial neuropathies appear. Clinical evidence of glandular in volvement is often minimal or absent when patients with SS develop peripheral neuropathy; and the diagnosis of the underlying condition is elusive. We review clinical and laboratory features of this disorder and suggest appropriate evaluation of patients with neuropathy and suspected SS.

Original languageEnglish (US)
Pages (from-to)570-579
Number of pages10
JournalMuscle & Nerve
Issue number7
StatePublished - Jul 1990


  • Sjogren' syndrome
  • distal polyneuropathy
  • mononeuropathy multiplex
  • peripheral neuropathy
  • subacute sensory neuropathy

ASJC Scopus subject areas

  • Physiology
  • Clinical Neurology
  • Cellular and Molecular Neuroscience
  • Physiology (medical)


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