Intrathoracic lymphadenopathy in patients with empyema

Linda B. Haramati, Daniel D. Alterman, Charles S. White, Andrew S. Kerr

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Purpose: Our goal was to determine the prevalence of intrathoracic lymphadenopathy on chest CT in patients with empyema. Method: We retrospectively identified 27 patients (14 men, 13 women, mean age 43 years) with nontuberculous empyema examined with chest CT. All scans were reviewed by two of three hoard-certified radiologists for the presence of intrathoracic lymphadenopathy (≤1 cm, short axis) in an American Thoracic Society (ATS) nodal station or the internal mammary region. Differences were resolved by consensus. Results: Thirteen (48%) patients with empyema had lymphadenopathy on chest CT. The mean number of enlarged lymph nodes for the patients with lymphadenopathy was 3.2 (SD ±2.3, range 1-8). The mean size of the largest lymph node was 1.4 cm (range 1.0-2.5 cm). The lymphadenopathy was unilateral and ipsilateral to the empyema in seven (54%), bilateral in five (38%), and unilateral contralateral to the empyema in one. The distribution of lymphadenopathy according to ATS nodal stations was 4R (n = 8), 7 (n = 6), 10R (n = 5); n = 2 each 2R, 10L, 11L; and n = 1 each 11R, 2L, 4L, and 6. Four patients had internal mammary lymphadenopathy. Pleural fluid and smooth pleural thickening were present in each case. Four patients had follow-up CT after treatment. There was a decrease or resolution of the lymphadenopathy in each case. Conclusion: Intrathoracic lymphadenopathy is a common CT finding in patients with empyema and occurred in 48% of this series. In patients with smooth pleural thickening and pleural effusion, intrathoracic lymphadenopathy should not be used as a criterion to differentiate empyema from malignant or tuberculous pleural effusion.

Original languageEnglish (US)
Pages (from-to)608-611
Number of pages4
JournalJournal of computer assisted tomography
Issue number4
StatePublished - 1997


  • Computed tomography
  • Empyema
  • Lungs, diseases
  • Lymph nodes, abnormalities
  • Thorax

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


Dive into the research topics of 'Intrathoracic lymphadenopathy in patients with empyema'. Together they form a unique fingerprint.

Cite this