TY - JOUR
T1 - Infectious Mimics of Inflammatory Bowel Disease
AU - Panarelli, Nicole C.
N1 - Publisher Copyright:
© 2023 United States & Canadian Academy of Pathology
PY - 2023/7
Y1 - 2023/7
N2 - Distinguishing inflammatory bowel disease (IBD) from its mimics remains a diagnostic challenge for surgical pathologists. Several gastrointestinal infections produce inflammatory patterns that overlap with typical findings of IBD. Although stool culture, PCR, and other clinical assays may identify infectious enterocolitides, these tests may not be performed or the results may be unavailable at the time of histologic evaluation. Furthermore, some clinical tests, including stool PCR, may reflect past exposure rather than an ongoing infection. It is important for surgical pathologists to be knowledgeable about infections that simulate IBD to generate an accurate differential diagnosis, perform appropriate ancillary studies, and prompt clinical follow-up. This review covers bacterial, fungal, and protozoal infections in the differential diagnosis of IBD.
AB - Distinguishing inflammatory bowel disease (IBD) from its mimics remains a diagnostic challenge for surgical pathologists. Several gastrointestinal infections produce inflammatory patterns that overlap with typical findings of IBD. Although stool culture, PCR, and other clinical assays may identify infectious enterocolitides, these tests may not be performed or the results may be unavailable at the time of histologic evaluation. Furthermore, some clinical tests, including stool PCR, may reflect past exposure rather than an ongoing infection. It is important for surgical pathologists to be knowledgeable about infections that simulate IBD to generate an accurate differential diagnosis, perform appropriate ancillary studies, and prompt clinical follow-up. This review covers bacterial, fungal, and protozoal infections in the differential diagnosis of IBD.
KW - Basidiobolus ranarum
KW - Entamoeba histolytica
KW - bacteria
KW - fungus
KW - inflammatory bowel disease
UR - http://www.scopus.com/inward/record.url?scp=85165521740&partnerID=8YFLogxK
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U2 - 10.1016/j.modpat.2023.100210
DO - 10.1016/j.modpat.2023.100210
M3 - Review article
C2 - 37172904
AN - SCOPUS:85165521740
SN - 0893-3952
VL - 36
JO - Modern Pathology
JF - Modern Pathology
IS - 7
M1 - 100210
ER -