Incidence of atrial fibrillation after mild or moderate hypothermic cardiopulmonary bypass

David C. Adams, Eric J. Heyer, Alan E. Simon, Ellise Delphin, Eric A. Rose, Mehmet C. Oz, Donald J. McMahon, Lena S. Sun

Research output: Contribution to journalArticlepeer-review

33 Scopus citations


Objectives: Atrial fibrillation remains a significant source of morbidity after coronary artery bypass grafting (CABG). Whether cardiopulmonary bypass (CPB) temperature influences the occurrence of postoperative atrial fibrillation in CABG patients has not been specifically examined. In the present study, we reviewed postoperative data from patients who were prospectively randomized to mild or moderate hypothermic CPB for elective CABG to determine the incidence of postoperative atrial fibrillation. Design: Randomized, single center, observational study. Setting: Tertiary university medical center. Patients: Adults undergoing elective CABG surgery. Interventions: Enrolled patients were prospectively randomized to mild (34°C [93.2°F]) or moderate (28°C [82.4°F]) hypothermic CPB. Measurements and Main Results: The incidence of postoperative atrial fibrillation was determined by review of ICU and hospital records. There was a significantly higher incidence of atrial fibrillation in the moderate compared with the mild hypothermic CPB group. Patients who had postoperative atrial fibrillation were significantly older than those without atrial fibrillation. Furthermore, a significant increase in the relative risk of developing postoperative atrial fibrillation was found for both age and CPB temperature. Conclusions: Our results indicate that the temperature of systemic cooling during CPB is an important factor in the development of atrial fibrillation after CABG surgery. In addition, this study confirms that increasing age is a significant determinant of postoperative atrial fibrillation.

Original languageEnglish (US)
Pages (from-to)309-311
Number of pages3
JournalCritical care medicine
Issue number2
StatePublished - 2000
Externally publishedYes


  • Adult
  • Aged
  • Arrhythmia
  • Atrial fibrillation
  • Cardiopulmonary bypass
  • Coronary artery bypass grafting
  • Hypothermia
  • Outcome
  • Risk factors
  • Sympathetic response

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine


Dive into the research topics of 'Incidence of atrial fibrillation after mild or moderate hypothermic cardiopulmonary bypass'. Together they form a unique fingerprint.

Cite this