TY - JOUR
T1 - Imaging of pulmonary hypertension in adults
T2 - A position paper from the fleischner society
AU - Remy-Jardin, Martine
AU - Ryerson, Christopher J.
AU - Schiebler, Mark L.
AU - Leung, Ann N.C.
AU - Wild, James M.
AU - Hoeper, Marius M.
AU - Alderson, Philip O.
AU - Goodman, Lawrence R.
AU - Mayo, John
AU - Haramati, Linda B.
AU - Ohno, Yoshiharu
AU - Thistlethwaite, Patricia
AU - van Beek, Edwin J.R.
AU - Lee Knight, Shandra
AU - Lynch, David A.
AU - Rubin, Geoffrey D.
AU - Humbert, Marc
N1 - Funding Information:
M.H. supported by the Investissement d’Avenir program managed by the French National Research Agency under the grant contract ANR-18-RHUS-0006 (DESTINATION 2024).
Funding Information:
Author contributions: Guarantors of integrity of entire study, M.R.J., Y.O., M.H.; study concepts/study design or data acquisition or data analysis/interpretation, all authors; manuscript drafting or manuscript revision for important intellectual content, all authors; approval of final version of submitted manuscript, all authors; agrees to ensure any questions related to the work are appropriately resolved, all authors; literature research, all authors; clinical studies, L.R.G., G.D.R.; statistical analysis, C.J.R., P.O.A., L.R.G., P.T.; and manuscript editing, all authors Disclosures of Conflicts of Interest: M.R.J. Activities related to the present article: disclosed no relevant relationships. Activities not related to the present article: received payment for lectures including service on speakers bureaus from Siemens Healthineers, Boehringer Ingelheim, Roche, and MSD. Other relationships: disclosed no relevant relationships. C.J.R. disclosed no relevant relationships. M.L.S. disclosed no relevant relationships. A.N.C.L. disclosed no relevant relationships. J.M.W. disclosed no relevant relationships. M.M.H. Activities related to the present article: disclosed no relevant relationships. Activities not related to the present article: is board member and consultant for Acceleron, Actelion, Bayer, Janssen, MSD, and Pfizer; received payment for lectures including service on speakers bureaus from Acceleron, Actelion, Bayer, Janssen, MSD, and Pfizer. Other relationships: disclosed no relevant relationships. P.O.A. disclosed no relevant relationships. L.R.G. disclosed no relevant relationships. J.M. Activities related to the present article: disclosed no relevant relationships. Activities not related to the present article: received payment for lectures including service on speakers bureaus from Siemens Healthineers Canada. Other relationships: disclosed no relevant relationships. L.B.H. disclosed no relevant relationships. Y.O. Activities related to the present article: received research grant from Canon Medical Systems. Activities not related to the present article: has grants/grants pending with Bayer Pharma. Other relationships: received Grants-in-Aid for Scientific Research from the Japanese Ministry of Education, Culture, Sports, Science and Technology; received research grant from Smoking Research Foundation; received research grant from Daiichi Sankyo. P.T. disclosed no relevant relationships. E.J.R.v.B. Activities related to the present article: disclosed no relevant relationships. Activities not related to the present article: is board member of Aidence, Imbio, and QCTIS; is a consultant for InHealth and Mentholatum. Other relationships: is owner and founder of QCTIS; author and spouse are directors. S.L.K. disclosed no relevant relationships. D.A.L. Activities related to the present article: disclosed no relevant relationships. Activities not related to the present article: is a consultant for
Publisher Copyright:
© 2021 RSNA and the European Respiratory Society.
PY - 2021/3
Y1 - 2021/3
N2 - Pulmonary hypertension (PH) is defined by a mean pulmonary artery pressure greater than 20 mm Hg and classified into five different groups sharing similar pathophysiologic mechanisms, hemodynamic characteristics, and therapeutic management. Radiologists play a key role in the multidisciplinary assessment and management of PH. A working group was formed from within the Fleischner Society based on expertise in the imaging and/or management of patients with PH, as well as experience with methodologies of systematic reviews. The working group identified key questions focusing on the utility of CT, MRI, and nuclear medicine in the evaluation of PH: (a) Is noninvasive imaging capable of identifying PH? (b) What is the role of imaging in establishing the cause of PH? (c) How does imaging determine the severity and complications of PH? (d) How should imaging be used to assess chronic thromboembolic PH before treatment? (e) Should imaging be performed after treatment of PH? This systematic review and position paper highlights the key role of imaging in the recognition, work-up, treatment planning, and follow-up of PH.
AB - Pulmonary hypertension (PH) is defined by a mean pulmonary artery pressure greater than 20 mm Hg and classified into five different groups sharing similar pathophysiologic mechanisms, hemodynamic characteristics, and therapeutic management. Radiologists play a key role in the multidisciplinary assessment and management of PH. A working group was formed from within the Fleischner Society based on expertise in the imaging and/or management of patients with PH, as well as experience with methodologies of systematic reviews. The working group identified key questions focusing on the utility of CT, MRI, and nuclear medicine in the evaluation of PH: (a) Is noninvasive imaging capable of identifying PH? (b) What is the role of imaging in establishing the cause of PH? (c) How does imaging determine the severity and complications of PH? (d) How should imaging be used to assess chronic thromboembolic PH before treatment? (e) Should imaging be performed after treatment of PH? This systematic review and position paper highlights the key role of imaging in the recognition, work-up, treatment planning, and follow-up of PH.
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U2 - 10.1148/radiol.2020203108
DO - 10.1148/radiol.2020203108
M3 - Article
C2 - 33399507
AN - SCOPUS:85101919102
SN - 0033-8419
VL - 298
SP - 531
EP - 549
JO - RADIOLOGY
JF - RADIOLOGY
IS - 3
ER -