Hypertension in connexin40-null mice: A renin disorder

D. C. Spray

doi:10.1038/sj.ki.5002515

Hypertension in connexin40-null mice: A renin disorder

D. C. Spray

Neuroscience

Research output: Contribution to journal › Comment/debate › peer-review

2 Scopus citations

Abstract

Studies described in this issue indicate that the gap junction protein connexin40 (Cx40) appears to play an unexpected role in blood pressure regulation. In mice lacking this gap junction protein, renin secretion is high and not regulated by arteriolar pressure.

Original language	English (US)
Pages (from-to)	781-782
Number of pages	2
Journal	Kidney international
Volume	72
Issue number	7
DOIs	https://doi.org/10.1038/sj.ki.5002515
State	Published - Oct 2007

ASJC Scopus subject areas

Nephrology

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title = "Hypertension in connexin40-null mice: A renin disorder",

abstract = "Studies described in this issue indicate that the gap junction protein connexin40 (Cx40) appears to play an unexpected role in blood pressure regulation. In mice lacking this gap junction protein, renin secretion is high and not regulated by arteriolar pressure.",

author = "Spray, {D. C.}",

note = "Funding Information: Research of the author's laboratory is supported by grants from the National Institutes of Health.",

year = "2007",

month = oct,

doi = "10.1038/sj.ki.5002515",

language = "English (US)",

volume = "72",

pages = "781--782",

journal = "Kidney international",

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T1 - Hypertension in connexin40-null mice

T2 - A renin disorder

AU - Spray, D. C.

N1 - Funding Information: Research of the author's laboratory is supported by grants from the National Institutes of Health.

PY - 2007/10

Y1 - 2007/10

N2 - Studies described in this issue indicate that the gap junction protein connexin40 (Cx40) appears to play an unexpected role in blood pressure regulation. In mice lacking this gap junction protein, renin secretion is high and not regulated by arteriolar pressure.

AB - Studies described in this issue indicate that the gap junction protein connexin40 (Cx40) appears to play an unexpected role in blood pressure regulation. In mice lacking this gap junction protein, renin secretion is high and not regulated by arteriolar pressure.

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U2 - 10.1038/sj.ki.5002515

DO - 10.1038/sj.ki.5002515

M3 - Comment/debate

C2 - 17882239

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SN - 0085-2538

VL - 72

SP - 781

EP - 782

JO - Kidney international

JF - Kidney international

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ER -

Hypertension in connexin40-null mice: A renin disorder

Abstract

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