HIV and pulmonary hypertension: A review

Sridhar Mani, G. J.Walker Smith

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


We describe two unique cases of pulmonary hypertension in association with the human immunodeficiency virus (HIV) and review the 28 previously reported cases in the world literature. Our first patient has coexistent chronic active hepatitis, which has previously been associated with the development of plexogenic pulmonary hypertension; however, our second case clearly demonstrates a closer link between HIV infection and pulmonary hypertension. Unlike previously reported cases, our latter case was devoid of all other coexistent factors including intravenous drug abuse, hepatitis B antigenemia, coexisting immunologic lung parenchymal injury, and hepatitis. Additionally, this is the first case documenting the presence of asymptomatic type II cryoglobulins in an HIVpositive patient with plexogenic pulmonary hypertension.

Original languageEnglish (US)
Pages (from-to)357-362
Number of pages6
JournalSouthern Medical Journal
Issue number3
StatePublished - Mar 1994
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


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