Hirano bodies in myelinated fibers of hepatic encephalopathy

K. Okamoto, S. Hiral, A. Hirano

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


Inclusions, essentially identical to Hirano bodies, were observed in the substantia nigra, dentate nuclei, and frontal lobes in three autopsy cases of hepatic encephalopathy. Similar inclusions were not observed in these areas in nine controls. The inclusions were mainly seen in the inner loops of the myelinated fibers, between the myelin lamellae, and among degenerated myelin sheaths. The same inclusions were rarely observed in postsynaptic terminals.

Original languageEnglish (US)
Pages (from-to)307-310
Number of pages4
JournalActa neuropathologica
Issue number4
StatePublished - Dec 1982
Externally publishedYes


  • Electron microscopy
  • Hepatic encephalopathy
  • Hirano body
  • Oligodendroglia

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Clinical Neurology
  • Cellular and Molecular Neuroscience


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