HHV-8 and AIDS-related CNS lymphoma

Susan Morgello; Michele Tagliati; Michelle R. Ewart

doi:10.1212/WNL.48.5.1333

HHV-8 and AIDS-related CNS lymphoma

Susan Morgello, Michele Tagliati, Michelle R. Ewart

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

Human herpesvirus 8 (HHV-8), the Kaposi's sarcoma (KS)-associated herpesvirus, is closely related to the transforming Epstein-Barr virus (EBV) and may be detected in AIDS-related, EBV-containing, body-cavity-based lymphomas. Accordingly, we analyzed 27 EBV-positive, AIDS-related CNS lymphomas for HHV-8 sequences. Only one tumor yielded HHV-8 sequences; this tumor arose in a patient with concomitant systemic lymphoma and a history of KS. We conclude that HHV-8 is unlikely to have a major role in the pathogenesis of AIDS-related, EBV-associated CNS lymphomas.

Original language	English (US)
Pages (from-to)	1333-1335
Number of pages	3
Journal	Neurology
Volume	48
Issue number	5
DOIs	https://doi.org/10.1212/WNL.48.5.1333
State	Published - May 1997
Externally published	Yes

ASJC Scopus subject areas

Clinical Neurology

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10.1212/WNL.48.5.1333

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title = "HHV-8 and AIDS-related CNS lymphoma",

abstract = "Human herpesvirus 8 (HHV-8), the Kaposi's sarcoma (KS)-associated herpesvirus, is closely related to the transforming Epstein-Barr virus (EBV) and may be detected in AIDS-related, EBV-containing, body-cavity-based lymphomas. Accordingly, we analyzed 27 EBV-positive, AIDS-related CNS lymphomas for HHV-8 sequences. Only one tumor yielded HHV-8 sequences; this tumor arose in a patient with concomitant systemic lymphoma and a history of KS. We conclude that HHV-8 is unlikely to have a major role in the pathogenesis of AIDS-related, EBV-associated CNS lymphomas.",

author = "Susan Morgello and Michele Tagliati and Ewart, {Michelle R.}",

year = "1997",

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T1 - HHV-8 and AIDS-related CNS lymphoma

AU - Morgello, Susan

AU - Tagliati, Michele

AU - Ewart, Michelle R.

PY - 1997/5

Y1 - 1997/5

N2 - Human herpesvirus 8 (HHV-8), the Kaposi's sarcoma (KS)-associated herpesvirus, is closely related to the transforming Epstein-Barr virus (EBV) and may be detected in AIDS-related, EBV-containing, body-cavity-based lymphomas. Accordingly, we analyzed 27 EBV-positive, AIDS-related CNS lymphomas for HHV-8 sequences. Only one tumor yielded HHV-8 sequences; this tumor arose in a patient with concomitant systemic lymphoma and a history of KS. We conclude that HHV-8 is unlikely to have a major role in the pathogenesis of AIDS-related, EBV-associated CNS lymphomas.

AB - Human herpesvirus 8 (HHV-8), the Kaposi's sarcoma (KS)-associated herpesvirus, is closely related to the transforming Epstein-Barr virus (EBV) and may be detected in AIDS-related, EBV-containing, body-cavity-based lymphomas. Accordingly, we analyzed 27 EBV-positive, AIDS-related CNS lymphomas for HHV-8 sequences. Only one tumor yielded HHV-8 sequences; this tumor arose in a patient with concomitant systemic lymphoma and a history of KS. We conclude that HHV-8 is unlikely to have a major role in the pathogenesis of AIDS-related, EBV-associated CNS lymphomas.

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SP - 1333

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JO - Neurology

JF - Neurology

IS - 5

ER -

HHV-8 and AIDS-related CNS lymphoma

Abstract

ASJC Scopus subject areas

UN SDGs

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