Hepatic Disorders in the Acquired Immune Deficiency Syndrome: A Clinical and Pathological Study

Sarah A. Kahn; Brian R. Saltzman; Robert S. Klein; Pana S. Mahadevia; Gerald H. Friedland; Lawrence J. Brandt

doi:10.1111/j.1572-0241.1986.tb01410.x

Hepatic Disorders in the Acquired Immune Deficiency Syndrome: A Clinical and Pathological Study

Sarah A. Kahn, Brian R. Saltzman, Robert S. Klein, Pana S. Mahadevia, Gerald H. Friedland, Lawrence J. Brandt

Medicine

Research output: Contribution to journal › Article › peer-review

60 Scopus citations

Abstract

We reviewed the clinical data, hepatic histology, and microbiological features of 21 patients with previously documented acquired immune deficiency syndrome who had liver biopsies. Diagnoses of specific infections were made on liver biopsy in 11/21 patients (57%). Granulomas were found in 10/21 patients (48%) and were most often a manifestation of infection with Mycobacteriam avium‐intracellulare. Elevated levels of serum alkaline phosphatase and longer duration of diagnosed illness were significantly associated with the presence of granulomatous disease.

Original language	English (US)
Pages (from-to)	1145-1148
Number of pages	4
Journal	The American Journal of Gastroenterology
Volume	81
Issue number	12
DOIs	https://doi.org/10.1111/j.1572-0241.1986.tb01410.x
State	Published - Dec 1986

ASJC Scopus subject areas

Hepatology
Gastroenterology

Access to Document

10.1111/j.1572-0241.1986.tb01410.x

Cite this

@article{3c17229160454b6f848b0138c8b496b6,

title = "Hepatic Disorders in the Acquired Immune Deficiency Syndrome: A Clinical and Pathological Study",

abstract = "We reviewed the clinical data, hepatic histology, and microbiological features of 21 patients with previously documented acquired immune deficiency syndrome who had liver biopsies. Diagnoses of specific infections were made on liver biopsy in 11/21 patients (57%). Granulomas were found in 10/21 patients (48%) and were most often a manifestation of infection with Mycobacteriam avium‐intracellulare. Elevated levels of serum alkaline phosphatase and longer duration of diagnosed illness were significantly associated with the presence of granulomatous disease.",

author = "Kahn, {Sarah A.} and Saltzman, {Brian R.} and Klein, {Robert S.} and Mahadevia, {Pana S.} and Friedland, {Gerald H.} and Brandt, {Lawrence J.}",

year = "1986",

month = dec,

doi = "10.1111/j.1572-0241.1986.tb01410.x",

language = "English (US)",

volume = "81",

pages = "1145--1148",

journal = "The American Journal of Gastroenterology",

issn = "0002-9270",

publisher = "Nature Publishing Group",

number = "12",

}

TY - JOUR

T1 - Hepatic Disorders in the Acquired Immune Deficiency Syndrome

T2 - A Clinical and Pathological Study

AU - Kahn, Sarah A.

AU - Saltzman, Brian R.

AU - Klein, Robert S.

AU - Mahadevia, Pana S.

AU - Friedland, Gerald H.

AU - Brandt, Lawrence J.

PY - 1986/12

Y1 - 1986/12

N2 - We reviewed the clinical data, hepatic histology, and microbiological features of 21 patients with previously documented acquired immune deficiency syndrome who had liver biopsies. Diagnoses of specific infections were made on liver biopsy in 11/21 patients (57%). Granulomas were found in 10/21 patients (48%) and were most often a manifestation of infection with Mycobacteriam avium‐intracellulare. Elevated levels of serum alkaline phosphatase and longer duration of diagnosed illness were significantly associated with the presence of granulomatous disease.

AB - We reviewed the clinical data, hepatic histology, and microbiological features of 21 patients with previously documented acquired immune deficiency syndrome who had liver biopsies. Diagnoses of specific infections were made on liver biopsy in 11/21 patients (57%). Granulomas were found in 10/21 patients (48%) and were most often a manifestation of infection with Mycobacteriam avium‐intracellulare. Elevated levels of serum alkaline phosphatase and longer duration of diagnosed illness were significantly associated with the presence of granulomatous disease.

UR - http://www.scopus.com/inward/record.url?scp=0023010653&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023010653&partnerID=8YFLogxK

U2 - 10.1111/j.1572-0241.1986.tb01410.x

DO - 10.1111/j.1572-0241.1986.tb01410.x

M3 - Article

C2 - 3024481

AN - SCOPUS:0023010653

SN - 0002-9270

VL - 81

SP - 1145

EP - 1148

JO - The American Journal of Gastroenterology

JF - The American Journal of Gastroenterology

IS - 12

ER -

Hepatic Disorders in the Acquired Immune Deficiency Syndrome: A Clinical and Pathological Study

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this