Hemophilia

William Beau Mitchell; Christopher Walsh

doi:10.1016/B978-0-323-56738-1.00018-X

Hemophilia

William Beau Mitchell, Christopher Walsh

Pediatrics

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Hemophilia is an X-linked bleeding disorder resulting from loss or decrease of the clotting factors VIII or IX. These two factors play a critical role in thrombin generation during thrombus formation. This chapter reviews the roles of factors VIII and IX in coagulation, the clinical presentation of individuals with hemophilia, and their clinical and laboratory evaluation.

Original language	English (US)
Title of host publication	Atlas of Diagnostic Hematology
Publisher	Elsevier
Pages	360-367
Number of pages	8
ISBN (Electronic)	9780323567381
ISBN (Print)	9780323567343
DOIs	https://doi.org/10.1016/B978-0-323-56738-1.00018-X
State	Published - Jan 1 2020

Keywords

X-linked
bleeding disorder
coagulation
factor IX
factor VIII
hemarthrosis
hemophilia
intracranial hemorrhage

ASJC Scopus subject areas

General Medicine

Access to Document

10.1016/B978-0-323-56738-1.00018-X

Cite this

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title = "Hemophilia",

abstract = "Hemophilia is an X-linked bleeding disorder resulting from loss or decrease of the clotting factors VIII or IX. These two factors play a critical role in thrombin generation during thrombus formation. This chapter reviews the roles of factors VIII and IX in coagulation, the clinical presentation of individuals with hemophilia, and their clinical and laboratory evaluation.",

keywords = "X-linked, bleeding disorder, coagulation, factor IX, factor VIII, hemarthrosis, hemophilia, intracranial hemorrhage",

author = "Mitchell, {William Beau} and Christopher Walsh",

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AB - Hemophilia is an X-linked bleeding disorder resulting from loss or decrease of the clotting factors VIII or IX. These two factors play a critical role in thrombin generation during thrombus formation. This chapter reviews the roles of factors VIII and IX in coagulation, the clinical presentation of individuals with hemophilia, and their clinical and laboratory evaluation.

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KW - coagulation

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KW - factor VIII

KW - hemarthrosis

KW - hemophilia

KW - intracranial hemorrhage

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EP - 367

BT - Atlas of Diagnostic Hematology

PB - Elsevier

ER -

Hemophilia

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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