Hematogones: A review and update

Deborah W. Sevilla; Adriana I. Colovai; Foxwell N. Emmons; Govind Bhagat; Bachir Alobeid

doi:10.3109/10428190903370346

Hematogones: A review and update

Deborah W. Sevilla, Adriana I. Colovai, Foxwell N. Emmons, Govind Bhagat, Bachir Alobeid

Research output: Contribution to journal › Review article › peer-review

48 Scopus citations

Abstract

Our knowledge regarding the nature and function of 'hematogones' has evolved considerably, since the initial description more than 70 years ago. Once considered the 'mystery cells' of the bone marrow, major advances in immunology and flow cytometry have enabled us to better characterize these cells and recognize them as physiologic precursors of B-cells. In this review, we describe the morphologic and phenotypic characteristics and clinical relevance of hematogones, and report recent advances in our understanding and knowledge of these cells as they relate to physiologic and different pathologic conditions.

Original language	English (US)
Pages (from-to)	10-19
Number of pages	10
Journal	Leukemia and Lymphoma
Volume	51
Issue number	1
DOIs	https://doi.org/10.3109/10428190903370346
State	Published - Jan 2010
Externally published	Yes

Keywords

Aplastic anemia
Hematogones
Lymphoblasts
Myelodysplastic syndrome
Precursor B-cells
Review

ASJC Scopus subject areas

Hematology
Oncology
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3109/10428190903370346

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title = "Hematogones: A review and update",

abstract = "Our knowledge regarding the nature and function of 'hematogones' has evolved considerably, since the initial description more than 70 years ago. Once considered the 'mystery cells' of the bone marrow, major advances in immunology and flow cytometry have enabled us to better characterize these cells and recognize them as physiologic precursors of B-cells. In this review, we describe the morphologic and phenotypic characteristics and clinical relevance of hematogones, and report recent advances in our understanding and knowledge of these cells as they relate to physiologic and different pathologic conditions.",

keywords = "Aplastic anemia, Hematogones, Lymphoblasts, Myelodysplastic syndrome, Precursor B-cells, Review",

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AU - Sevilla, Deborah W.

AU - Colovai, Adriana I.

AU - Emmons, Foxwell N.

AU - Bhagat, Govind

AU - Alobeid, Bachir

PY - 2010/1

Y1 - 2010/1

N2 - Our knowledge regarding the nature and function of 'hematogones' has evolved considerably, since the initial description more than 70 years ago. Once considered the 'mystery cells' of the bone marrow, major advances in immunology and flow cytometry have enabled us to better characterize these cells and recognize them as physiologic precursors of B-cells. In this review, we describe the morphologic and phenotypic characteristics and clinical relevance of hematogones, and report recent advances in our understanding and knowledge of these cells as they relate to physiologic and different pathologic conditions.

AB - Our knowledge regarding the nature and function of 'hematogones' has evolved considerably, since the initial description more than 70 years ago. Once considered the 'mystery cells' of the bone marrow, major advances in immunology and flow cytometry have enabled us to better characterize these cells and recognize them as physiologic precursors of B-cells. In this review, we describe the morphologic and phenotypic characteristics and clinical relevance of hematogones, and report recent advances in our understanding and knowledge of these cells as they relate to physiologic and different pathologic conditions.

KW - Aplastic anemia

KW - Hematogones

KW - Lymphoblasts

KW - Myelodysplastic syndrome

KW - Precursor B-cells

KW - Review

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Hematogones: A review and update

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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