Health effects of low-carbohydrate diets: Where should new research go?

Judith Wylie-Rosett, Karin Aebersold, Beth Conlon, Carmen R. Isasi, Natania W. Ostrovsky

Research output: Contribution to journalArticlepeer-review

43 Scopus citations


There has been considerable debate about the metabolic effects of restricting carbohydrate intake in weight and diabetes management. However, the American Diabetes Association has noted that weight and metabolic improvements can be achieved with low carbohydrate, low fat (implicitly higher carbohydrate), or a Mediterranean style diet (usually an intermediate level of carbohydrate). Our paper addresses variability in the definition for low or restricted carbohydrate, the effects of carbohydrate restriction on diabetes-related health outcomes, strategies for restricting carbohydrate intake, and potential genetic variability in response to dietary carbohydrate restriction. Issues for future research are also addressed.

Original languageEnglish (US)
Pages (from-to)271-278
Number of pages8
JournalCurrent diabetes reports
Issue number2
StatePublished - Apr 2013


  • Available carbohydrate
  • Diabetes
  • Diet
  • Eating patterns
  • Genetic variability
  • Gut hormones
  • Health effects
  • Insulin resistance
  • Low carbohydrate
  • Nutrition
  • Nutrition guidelines
  • Paleolithic diet
  • Research

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism


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