Global aphasia without hemiparesis: Multiple etiologies

A. D. Legatt, M. J. Rubin, L. R. Kaplan, E. B. Healton, J. C.M. Brust

Research output: Contribution to journalArticlepeer-review

48 Scopus citations


Acute global aphasia without hemiparesis has been considered pathognomonic of embolic stroke. During 1 year, we encountered six patients with this syndrome. Two had multiple strokes, probably embolic. One had atrial fibrillation; at autopsy, there were metastases as well as multiple infarcts in the left hemisphere. One had a single large infarct in the territory of an anterior branch of the middle cerebral artery (MCA), one had subarachnoid hemorrhage of unknown origin, and one had a sylvian fissure hematoma with intraparenchymal extension from a ruptured MCA aneurysm. Nonembolic etiologies are therefore also possible and include conditions that bar anticoagulation.

Original languageEnglish (US)
Pages (from-to)201-205
Number of pages5
Issue number2
StatePublished - Feb 1987

ASJC Scopus subject areas

  • Clinical Neurology


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