@article{13c147a8523b4a2f928d890b3828d771,
title = "Germline variants drive myelodysplastic syndrome in young adults",
author = "Simone Feurstein and Churpek, {Jane E.} and Tom Walsh and Sioban Keel and Marja Hakkarainen and Thomas Schroeder and Ulrich Germing and Stefanie Geyh and Michael Heuser and Felicitas Thol and Christian Pohlkamp and Torsten Haferlach and Juehua Gao and Carolyn Owen and Gudrun Goehring and Brigitte Schlegelberger and Divij Verma and Krause, {Daniela S.} and Guimin Gao and Tara Cronin and Suleyman Gulsuner and Ming Lee and Pritchard, {Colin C.} and Subramanian, {Hari Prasanna} and {del Gaudio}, Daniela and Zejuan Li and Soma Das and Outi Kilpivaara and Ulla Wartiovaara-Kautto and Wang, {Eunice S.} and Griffiths, {Elizabeth A.} and Konstanze D{\"o}hner and Hartmut D{\"o}hner and King, {Mary Claire} and Godley, {Lucy A.}",
note = "Funding Information: Acknowledgements The authors would like to gratefully acknowledge all of the individuals who participated in this study and their physicians for submitting the clinical samples. We would also like to thank Michelle Le Beau and Ludmila Hill from the Cancer Cytogenetics Laboratory at The University of Chicago for providing viably frozen bone marrow samples. This study was supported by the Cancer Research Foundation and the Taub Foundation (L.A.G.), the intramural {\textquoteleft}Baustein{\textquoteright} program for Junior Scientists of the Medical Faculty of Ulm University, Ulm, Germany (S.F.), and the German Bundesministerium f{\"u}r Bildung und Forschung {\textquoteleft}MyPred{\textquoteright} (01GM1911B) (B.S., G.G.) and {\textquoteleft}ADDRess{\textquoteright} (01GM1909A) (G.G.) and the Cancer Society of Finland, the Children{\textquoteright}s Cancer Foundation V{\"a}re, and the Sigrid Juselius Foundation (M.H., O.K., U.W-K.). In addition, the NIH supported this work through: P30CA016056 (use of Roswell Park Comprehensive Cancer Center{\textquoteright}s Hematologic Procurement Shared Resource, E.W.), R03HL145253 (J.E.C.), R35CA197458 and R24DK099808 (M-C.K., T.W., S.G., M.L.). We would also like to acknowledge the input of Linda Lutgen-Dunckley, Brandon Martens, and Joseph Moberg from the Roswell Park Hematologic Procurement Shared Resource (CIC 98-05) for providing samples supported by the Cancer Center Support Grant at Roswell Park (2P30CA016056-42). M-C.K. is an American Cancer Society Professor. Funding Information: Conflict of interest We declare the following conflicts of interest: TW consults for Color Genomics. TH is part owner of the Munich Leukemia Laboratory. EAG has received honoraria/advisory board payments from Alexion Pharmaceuticals, Celgene/BMS, AbbVie, and Novartis. EAG has also received institutional research funding from Genentech Inc., Appelis pharmaceuticals, Celldex Therapeutics, and Celgene/BMS. CO has received honoraria/advisory board payments from AbbVie, AstraZeneca, Janssen, Roche, and Novartis. LAG and JEC have received honoraria from UptoDate, Inc. LAG has received advisory board payments from Invitae, Inc.",
year = "2021",
month = aug,
doi = "10.1038/s41375-021-01137-0",
language = "English (US)",
volume = "35",
pages = "2439--2444",
journal = "Leukemia",
issn = "0887-6924",
publisher = "Nature Publishing Group",
number = "8",
}
