Genomics for health in preconception and prenatal periods: Genomics to health

Siobhan Dolan, Janis Biermann, Karla Damus

Research output: Contribution to journalReview articlepeer-review

16 Scopus citations


Purpose: To review and report changes in genomic-based knowledge and care during the preconception and prenatal periods. Design: Integrative review of relevant medical and nursing literature. Findings: Client education and counseling are needed to understand genomic information and provide guidance in interpreting this information and making decisions. The factors that influence decision-making about testing and acting on test results constitute a complex process that has not been well studied. Family history is an important tool for obtaining genomic information and can assist women and families in understanding risk preconceptionally and prenatally. Genomic research has enhanced understanding of the mechanisms of birth defects such as neural tube defect and will likely provide research opportunities to better understand complex perinatal outcomes such as preterm birth. Conclusions: Research, education, advocacy, and anticipatory guidance are needed as women and families obtain more genetic and genomic information before and during pregnancy. All nurses will be involved in helping patients use genetic and genomic information to understand risk and to develop strategies to modify risk, and in translating the expanding array of genomic information to improve birth outcomes.

Original languageEnglish (US)
Pages (from-to)4-9
Number of pages6
JournalJournal of Nursing Scholarship
Issue number1
StatePublished - Jan 2007


  • Genetic testing
  • Genomics
  • Preconception
  • Prenatal
  • Screening

ASJC Scopus subject areas

  • General Nursing


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