TY - JOUR
T1 - Fungal infections in children with human immunodeficiency virus infection
AU - Pirofski, Liise Anne
N1 - Funding Information:
Supported by National Institutes of Health research Grants AI RO1 35370, AI RO1 49459, and AI RO1 44374.
Copyright:
Copyright 2018 Elsevier B.V., All rights reserved.
PY - 2001
Y1 - 2001
N2 - The increasing prevalence of fungal infections is caused in large part by the human immunodeficiency virus (HIV) epidemic. HIV-associated immunodeficiency is a major risk factor for invasive fungal disease. The prevalence of fungal infections in adults with HIV infection is markedly increased, and a large body of information about their incidence, course, and prognosis in adults exists. However, fungal infections, except candidiasis, are less common in children with HIV infection, and information about their pathogenesis is limited. The reason for this difference is unknown. This article reviews the occurrence of systemic fungal infections in children with HIV infection. Despite the relative rarity of infections with the ubiquitous and endemic fungi in the first 2 decades of the HIV epidemic, the increasing number of children with longstanding HIV infection in the era of highly active antiretroviral therapy warrants close surveillance for and aggressive treatment of fungal infections in children with HIV infection.
AB - The increasing prevalence of fungal infections is caused in large part by the human immunodeficiency virus (HIV) epidemic. HIV-associated immunodeficiency is a major risk factor for invasive fungal disease. The prevalence of fungal infections in adults with HIV infection is markedly increased, and a large body of information about their incidence, course, and prognosis in adults exists. However, fungal infections, except candidiasis, are less common in children with HIV infection, and information about their pathogenesis is limited. The reason for this difference is unknown. This article reviews the occurrence of systemic fungal infections in children with HIV infection. Despite the relative rarity of infections with the ubiquitous and endemic fungi in the first 2 decades of the HIV epidemic, the increasing number of children with longstanding HIV infection in the era of highly active antiretroviral therapy warrants close surveillance for and aggressive treatment of fungal infections in children with HIV infection.
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U2 - 10.1053/spid.2001.26636
DO - 10.1053/spid.2001.26636
M3 - Article
AN - SCOPUS:0034749805
SN - 1045-1870
VL - 12
SP - 288
EP - 295
JO - Seminars in Pediatric Infectious Diseases
JF - Seminars in Pediatric Infectious Diseases
IS - 4
ER -