Functional significance of alterations in cardiac contractile protein isoforms

Richard N. Kitsis; James Scheuer

doi:10.1002/clc.4960190105

Functional significance of alterations in cardiac contractile protein isoforms

Richard N. Kitsis, James Scheuer

Medicine

Research output: Contribution to journal › Review article › peer-review

9 Scopus citations

Abstract

Multiple closely related, yet distinct, isoforms exist for each of the cardiac contractile proteins. The isoform composition of the heart changes in response to developmental and physiologic cues. This paper reviews the molecular basis for cardiac contractile protein isoform diversity and the functional consequences of isoform shifts.

Original language	English (US)
Pages (from-to)	9-18
Number of pages	10
Journal	Clinical Cardiology
Volume	19
Issue number	1
DOIs	https://doi.org/10.1002/clc.4960190105
State	Published - Jan 1996

Keywords

cardiac function
contractile proteins
heart failure

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1002/clc.4960190105

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title = "Functional significance of alterations in cardiac contractile protein isoforms",

abstract = "Multiple closely related, yet distinct, isoforms exist for each of the cardiac contractile proteins. The isoform composition of the heart changes in response to developmental and physiologic cues. This paper reviews the molecular basis for cardiac contractile protein isoform diversity and the functional consequences of isoform shifts.",

keywords = "cardiac function, contractile proteins, heart failure",

author = "Kitsis, {Richard N.} and James Scheuer",

year = "1996",

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KW - contractile proteins

KW - heart failure

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DO - 10.1002/clc.4960190105

M3 - Review article

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AN - SCOPUS:0029789798

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SP - 9

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JO - Clinical Cardiology

JF - Clinical Cardiology

IS - 1

ER -

Functional significance of alterations in cardiac contractile protein isoforms

Abstract

Keywords

ASJC Scopus subject areas

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