Functional significance of alterations in cardiac contractile protein isoforms

Richard N. Kitsis, James Scheuer

Research output: Contribution to journalReview articlepeer-review

9 Scopus citations


Multiple closely related, yet distinct, isoforms exist for each of the cardiac contractile proteins. The isoform composition of the heart changes in response to developmental and physiologic cues. This paper reviews the molecular basis for cardiac contractile protein isoform diversity and the functional consequences of isoform shifts.

Original languageEnglish (US)
Pages (from-to)9-18
Number of pages10
JournalClinical Cardiology
Issue number1
StatePublished - Jan 1996


  • cardiac function
  • contractile proteins
  • heart failure

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


Dive into the research topics of 'Functional significance of alterations in cardiac contractile protein isoforms'. Together they form a unique fingerprint.

Cite this