Abstract
Emerging evidence has shown that microRNAs (miRNAs) play critical role in the pathogenesis of several disorders. In the present minireview, we focus our attention on the functional role of a specific miRNA, namely miR-34a, in the pathophysiology of frailty and diabetes mellitus. Based on the current literature, we speculate that this miRNA may serve as a potential biomarker of frailty in diabetic older adults. Additionally, its actions on oxidative stress might represent a druggable target to obtain new potentials treatments.
Original language | English (US) |
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Article number | 949924 |
Journal | Frontiers in Aging |
Volume | 3 |
DOIs | |
State | Published - 2022 |
Keywords
- aging
- diabetes
- frailty
- miR-34
- miRNA
ASJC Scopus subject areas
- Aging
- Genetics
- Molecular Biology
- Physiology