Functional ribosomal unit of gamma-globulin synthesis

Matthew D. Scharff; Jonathan W. Uhr

doi:10.1126/science.148.3670.646

Functional ribosomal unit of gamma-globulin synthesis

Matthew D. Scharff, Jonathan W. Uhr

Cell Biology

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Nascent protein synthesis is associated with polyribosomes in extracts of lymph node cells removed from hyperimmunized rabbits, if the ribonuclease activity in such extracts is inhibited. Prior treatment of the cells with actinomycin D markedly decreases protein synthesis by polyribosomes.

Original language	English (US)
Pages (from-to)	646-648
Number of pages	3
Journal	Science
Volume	148
Issue number	3670
DOIs	https://doi.org/10.1126/science.148.3670.646
State	Published - Jan 1 1965

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title = "Functional ribosomal unit of gamma-globulin synthesis",

abstract = "Nascent protein synthesis is associated with polyribosomes in extracts of lymph node cells removed from hyperimmunized rabbits, if the ribonuclease activity in such extracts is inhibited. Prior treatment of the cells with actinomycin D markedly decreases protein synthesis by polyribosomes.",

author = "Scharff, {Matthew D.} and Uhr, {Jonathan W.}",

year = "1965",

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doi = "10.1126/science.148.3670.646",

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AB - Nascent protein synthesis is associated with polyribosomes in extracts of lymph node cells removed from hyperimmunized rabbits, if the ribonuclease activity in such extracts is inhibited. Prior treatment of the cells with actinomycin D markedly decreases protein synthesis by polyribosomes.

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Functional ribosomal unit of gamma-globulin synthesis

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