Abstract
Objective The objective of the study was to compare the 3-dimensional power Doppler (3DPD) of the uteroplacental circulation space in the first trimester between women who subsequently deliver growth-restricted vs normally grown neonates. Study Design This was a prospective observational study of singleton pregnancies at 11-14 weeks' gestation. The 3DPD indices, vascularization index, flow index, and vascularization flow index were determined on a uteroplacental circulation space sphere biopsy with the virtual organ computer-aided analysis program. Growth restriction was defined as a birthweight less than the 10th percentile for gestational age and was evaluated using both population-based and customized birth curves. Results Five hundred seventy-seven women were enrolled. Five hundred twenty-six were eligible for analysis using population centiles, and 497 were available for evaluation using customized centiles. There was no difference in the first-trimester 3DPD indices between patients with growth-restricted and normally grown neonates using either curve. Conclusion Three-dimensional power Doppler indices of the uteroplacental circulation space in the first trimester are similar between neonates who develop growth restriction and those who will grow normally.
Original language | English (US) |
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Pages (from-to) | 521.e1-521.e8 |
Journal | American journal of obstetrics and gynecology |
Volume | 211 |
Issue number | 5 |
DOIs | |
State | Published - Nov 1 2014 |
Keywords
- Doppler
- fetal growth restriction
- placenta
ASJC Scopus subject areas
- Obstetrics and Gynecology