Fine structure of anterior horns in patients without amyotrophic lateral sclerosis

Hlrofumi Kusaka, Asao Hirano

Research output: Contribution to journalArticlepeer-review

27 Scopus citations


Light and electron microscopic study of the anterior horns in nine patients without amyotrophic lateral sclerosis (ALS) disclosed several features usually de-scribed in ALS. Central chromatolysis and spheroids with fine structure identical to that seen in ALS were observed in three cases. Rare honeycomb-like structures, dense filamentous aggregates, dense granular deposits, stubby mitochondria and membrane-bound aggregates of spherical and tubular particles were also observed. No typical Bunina bodies or focal argyrophilia of the chromatolytic neurons were found.

Original languageEnglish (US)
Pages (from-to)430-438
Number of pages9
JournalJournal of Neuropathology and Experimental Neurology
Issue number4
StatePublished - Jul 1985
Externally publishedYes


  • Amyotrophic lateral sclerosis
  • Anterior horn
  • Central chromatolysis
  • Spheroid
  • Ultrastructure

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Neurology
  • Clinical Neurology
  • Cellular and Molecular Neuroscience


Dive into the research topics of 'Fine structure of anterior horns in patients without amyotrophic lateral sclerosis'. Together they form a unique fingerprint.

Cite this