Familial erythroleukemia: A distinct clinical and genetic type of familial leukemias

Yelena Novik, Patricia Marino, Della F. Makower, Peter H. Wiernik

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


A family with erythroleukemia is presented, in which father and son were diagnosed at the same age, but 20 years apart, with almost identical clinical and morphological features of the disease. No environmental factors were identified. The karyotypic abnormalities of the bone marrow blasts in the son demonstrated 2 major clones, involving chromosomes 5 and 7, as well as 8, 13, 16 and 21. Both patients demonstrated a poor response to chemotherapy. Previously described families with erythroleukemia are reviewed with available specific karyotypic aberrations.

Original languageEnglish (US)
Pages (from-to)395-401
Number of pages7
JournalLeukemia and Lymphoma
Issue number3-4
StatePublished - Jan 1 1998


  • Acute myelogenous leukemia
  • Erythroleukemia
  • Genetic predisposition
  • Karyotype

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research


Dive into the research topics of 'Familial erythroleukemia: A distinct clinical and genetic type of familial leukemias'. Together they form a unique fingerprint.

Cite this