Extraskeletal Ewing sarcoma of the parapharyngeal space with a unique translocation, t(19;22) (q13.4;q12.2)

Gloria Ramos-Rivera; Esther Adler; K. H. Ramesh; Bradley Schiff; Mark Suhrland; Samer Khader

doi:10.1016/j.ehpc.2015.07.003

Extraskeletal Ewing sarcoma of the parapharyngeal space with a unique translocation, t(19;22) (q13.4;q12.2)

Gloria Ramos-Rivera, Esther Adler, K. H. Ramesh, Bradley Schiff, Mark Suhrland, Samer Khader

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Extraskeletal Ewing sarcomas of the parapharyngeal space are extremely rare. It has been documented that Ewing sarcomas are morphologically and molecularly indistinguishable regardless of the tissue of origin. Around 85% of Ewing sarcomas are associated with translocation t(11;22)(q24.1;12.2) generating the EWSR1-FLI1 fusion oncoprotein. We report a case of an extraskeletal Ewing sarcoma arising in the parapharyngeal space with a unique translocation: t(19; 22) (q13.4;q12.2). To our knowledge this is the first case of an extraskeletal Ewing sarcoma exhibiting this translocation.

Original language	English (US)
Pages (from-to)	38-41
Number of pages	4
Journal	Human Pathology: Case Reports
Volume	4
DOIs	https://doi.org/10.1016/j.ehpc.2015.07.003
State	Published - Jun 1 2016

Keywords

Ewing sarcoma family of tumors
Extraskeletal Ewing sarcoma
Parapharyngeal space
T(19;22)(q13.4;q12.2)

ASJC Scopus subject areas

Pathology and Forensic Medicine

Access to Document

10.1016/j.ehpc.2015.07.003

Cite this

@article{42911b5fc0b0420e903c5fc884b0bb64,

title = "Extraskeletal Ewing sarcoma of the parapharyngeal space with a unique translocation, t(19;22) (q13.4;q12.2)",

abstract = "Extraskeletal Ewing sarcomas of the parapharyngeal space are extremely rare. It has been documented that Ewing sarcomas are morphologically and molecularly indistinguishable regardless of the tissue of origin. Around 85% of Ewing sarcomas are associated with translocation t(11;22)(q24.1;12.2) generating the EWSR1-FLI1 fusion oncoprotein. We report a case of an extraskeletal Ewing sarcoma arising in the parapharyngeal space with a unique translocation: t(19; 22) (q13.4;q12.2). To our knowledge this is the first case of an extraskeletal Ewing sarcoma exhibiting this translocation.",

keywords = "Ewing sarcoma family of tumors, Extraskeletal Ewing sarcoma, Parapharyngeal space, T(19;22)(q13.4;q12.2)",

author = "Gloria Ramos-Rivera and Esther Adler and Ramesh, {K. H.} and Bradley Schiff and Mark Suhrland and Samer Khader",

note = "Publisher Copyright: {\textcopyright} 2015 The Authors.",

year = "2016",

month = jun,

day = "1",

doi = "10.1016/j.ehpc.2015.07.003",

language = "English (US)",

volume = "4",

pages = "38--41",

journal = "Human Pathology: Case Reports",

issn = "2214-3300",

publisher = "Elsevier Inc.",

}

TY - JOUR

T1 - Extraskeletal Ewing sarcoma of the parapharyngeal space with a unique translocation, t(19;22) (q13.4;q12.2)

AU - Ramos-Rivera, Gloria

AU - Adler, Esther

AU - Ramesh, K. H.

AU - Schiff, Bradley

AU - Suhrland, Mark

AU - Khader, Samer

PY - 2016/6/1

Y1 - 2016/6/1

N2 - Extraskeletal Ewing sarcomas of the parapharyngeal space are extremely rare. It has been documented that Ewing sarcomas are morphologically and molecularly indistinguishable regardless of the tissue of origin. Around 85% of Ewing sarcomas are associated with translocation t(11;22)(q24.1;12.2) generating the EWSR1-FLI1 fusion oncoprotein. We report a case of an extraskeletal Ewing sarcoma arising in the parapharyngeal space with a unique translocation: t(19; 22) (q13.4;q12.2). To our knowledge this is the first case of an extraskeletal Ewing sarcoma exhibiting this translocation.

AB - Extraskeletal Ewing sarcomas of the parapharyngeal space are extremely rare. It has been documented that Ewing sarcomas are morphologically and molecularly indistinguishable regardless of the tissue of origin. Around 85% of Ewing sarcomas are associated with translocation t(11;22)(q24.1;12.2) generating the EWSR1-FLI1 fusion oncoprotein. We report a case of an extraskeletal Ewing sarcoma arising in the parapharyngeal space with a unique translocation: t(19; 22) (q13.4;q12.2). To our knowledge this is the first case of an extraskeletal Ewing sarcoma exhibiting this translocation.

KW - Ewing sarcoma family of tumors

KW - Extraskeletal Ewing sarcoma

KW - Parapharyngeal space

KW - T(19;22)(q13.4;q12.2)

UR - http://www.scopus.com/inward/record.url?scp=84940676365&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84940676365&partnerID=8YFLogxK

U2 - 10.1016/j.ehpc.2015.07.003

DO - 10.1016/j.ehpc.2015.07.003

M3 - Article

AN - SCOPUS:84940676365

SN - 2214-3300

VL - 4

SP - 38

EP - 41

JO - Human Pathology: Case Reports

JF - Human Pathology: Case Reports

ER -

Extraskeletal Ewing sarcoma of the parapharyngeal space with a unique translocation, t(19;22) (q13.4;q12.2)

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this