Extracorporeal membrane oxygenation and severe acute respiratory distress secondary to legionella: 10 year experience

Moronke A. Noah, Geethanjali Ramachandra, Margaret M. Hickey, David R. Jenkins, Chris J. Harvey, Claire A. Westrope, Richard K. Firmin, Giles J. Peek

Research output: Contribution to journalReview articlepeer-review

14 Scopus citations


Legionella-associated respiratory failure has a high mortality, despite modern ventilation modalities. Extracorporeal membrane oxygenation (ECMO) is used to achieve gas exchange independent of pulmonary function in patients with severe respiratory failure. This was a retrospective review of the management and outcome of patients with Legionella-associated respiratory failure treated with ECMO support in a large ECMO center over the past 10 years. A retrospective review of patients with confirmed Legionella-associated severe respiratory failure managed with ECMO support at a single center. Between 2000 and 2010, 19 patients with severe respiratory failure caused by Legionella were managed with ECMO after failure to respond to conventional intensive care management. Median PaO2/FiO2 ratio was 66 and median pCO2 was 60 torr. Sixteen patients (84%) survived to hospital discharge. Extracorporeal membrane oxygenation should be considered in patients with Legionella-associated respiratory failure, who have failed conventional ventilation.

Original languageEnglish (US)
Pages (from-to)328-330
Number of pages3
JournalASAIO Journal
Issue number3
StatePublished - May 2013
Externally publishedYes


  • Legionella
  • Legionnaire's disease
  • extracorporeal membrane oxygenation
  • severe respiratory failure

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering
  • Biomaterials
  • Biomedical Engineering


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