Extracellular dopamine potentiates Mn-induced oxidative stress, lifespan reduction, and dopaminergic neurodegeneration in a BLI-3-dependent manner in caenorhabditis elegans

Medicine & Life Sciences

• Manganese 88%
• Caenorhabditis elegans 81%
• Longevity 66%
• Dopamine 62%
• Parkinson Disease 61%
• Oxidative Stress 54%
• Parkinson Disease 8 21%
• Dual Oxidases 20%
• Dopamine Plasma Membrane Transport Proteins 15%
• NADPH Oxidases 14%
• Pesticides 13%
• Environmental Exposure 13%
• Dopaminergic Neurons 12%
• Molecular Biology 9%
• Genes 9%
• Cell Culture Techniques 9%
• Transcription Factors 9%
• Poisons 9%
• Antioxidants 9%
• Mutation 6%
• Pharmaceutical Preparations 5%

Agriculture & Biology

• Parkinson disease 100%
• Caenorhabditis elegans 77%
• dopamine 73%
• manganese 69%
• oxidative stress 58%
• toxicity 21%
• disease occurrence 13%
• NAD(P)H oxidase (H2O2-forming) 12%
• risk factors 10%
• oxidants 10%
• NADP (coenzyme) 10%
• transporters 9%
• neurons 8%
• pesticides 8%
• cell culture 8%
• transcription factors 8%
• genes 7%
• mutation 7%
• drugs 7%
• assays 5%
• cells 3%

Earth & Environmental Sciences

• oxidative stress 85%
• manganese 66%
• toxicity 23%
• gene 16%
• cell 12%
• antioxidant 11%
• risk factor 10%
• mutation 10%
• pesticide 9%
• assay 8%
• exposure 6%