Experimental approaches to the study of epigenomic dysregulation in ageing

Research output: Contribution to journalShort surveypeer-review

16 Scopus citations


In this review, we describe how normal ageing may involve the acquisition of epigenetic errors over time, akin to the accumulation of genetic mutations with ageing. We describe how such experiments are currently performed, their limitations technically and analytically and their application to ageing research.

Original languageEnglish (US)
Pages (from-to)255-268
Number of pages14
JournalExperimental Gerontology
Issue number4
StatePublished - Apr 2010


  • Aging
  • Chromatin
  • DNA methylation
  • Epigenetic
  • Microarray

ASJC Scopus subject areas

  • Biochemistry
  • Aging
  • Molecular Biology
  • Genetics
  • Endocrinology
  • Cell Biology


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