TY - JOUR
T1 - Event-related potential correlates of early processing in normal aging
AU - Schroeder, Mary M.
AU - Lipton, Richard B.
AU - Ritter, Walter
AU - Giesser, Barbara S.
AU - Vaughan, Herbert G.
N1 - Funding Information:
This work was supported, in part, by PHS grants NS19234, HD10804, and MH15788.W e thank Dr. G. Novak for his helpful comments and Chester Freemen for technical assistance.
PY - 1995
Y1 - 1995
N2 - Auditory event-related potentials were recorded from normal elderly and young adult subjects during simple reaction time and discrimination conditions. In both response conditions, the stimuli were randomly presented, as in an auditory oddball" paradigm. It was found that NA, an index of early information processing, was significantly delayed in the elderly. Although the latency of Nl was not significantly different between the groups, the latencies of N2 and P3 were significantly longer for the aged subjects. The amplitudes of N1, NA1, NA2, and N2 showed no group differences. The raw amplitude of P3 showed a group difference in topography: Pz was greater than Fz for the young group, but not for the aged. When the amplitudes of NA 1, NA2, and P3 were scaled, however, the topography of these components showed no significant group differences. These findings suggest that the age-related slowing of later ERP components and behavior may be partially accounted for by delays in early attention dependent perceptual processes, as indexed by NA.
AB - Auditory event-related potentials were recorded from normal elderly and young adult subjects during simple reaction time and discrimination conditions. In both response conditions, the stimuli were randomly presented, as in an auditory oddball" paradigm. It was found that NA, an index of early information processing, was significantly delayed in the elderly. Although the latency of Nl was not significantly different between the groups, the latencies of N2 and P3 were significantly longer for the aged subjects. The amplitudes of N1, NA1, NA2, and N2 showed no group differences. The raw amplitude of P3 showed a group difference in topography: Pz was greater than Fz for the young group, but not for the aged. When the amplitudes of NA 1, NA2, and P3 were scaled, however, the topography of these components showed no significant group differences. These findings suggest that the age-related slowing of later ERP components and behavior may be partially accounted for by delays in early attention dependent perceptual processes, as indexed by NA.
KW - Aging
KW - Cognitive
KW - ERP
KW - Event-related potentials
KW - Information processing
KW - Topography
UR - http://www.scopus.com/inward/record.url?scp=0029190867&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0029190867&partnerID=8YFLogxK
U2 - 10.3109/00207459508986110
DO - 10.3109/00207459508986110
M3 - Article
C2 - 7775059
AN - SCOPUS:0029190867
SN - 0020-7454
VL - 80
SP - 371
EP - 382
JO - International Journal of Neuroscience
JF - International Journal of Neuroscience
IS - 1-4
ER -