TY - JOUR
T1 - Evaluation of a unilateral neck mass in a 16-year-old female
T2 - Kikuchi-Fujimoto disease with superimposed bacterial lymphadenitis
AU - Burns, Joseph
AU - Pathania, Shivany
AU - Griesser, Rebecca
AU - Norelli, Jolanta
AU - Gilgeours, Kelly
AU - Tugetman, Jessica
AU - Palumbo, Nancy
N1 - Publisher Copyright:
© The Author(s) 2020.
PY - 2020
Y1 - 2020
N2 - The evaluation of pediatric neck masses offers the opportunity for consideration of a diverse range of pathologies, from infectious to neoplastic. A 16-year-old female presented with 2 weeks of worsening swelling and pain of a left-sided neck mass. Findings were consistent with Epstein–Barr virus and cytomegalovirus coinfection, but considering profound lymphadenopathy of the supraclavicular, mammillary, and axillary chains, further investigations were undertaken. Hematopathologic examination demonstrated necrotizing lymphadenitis, consistent with Kikuchi-Fujimoto disease. A diagnosis of Kikuchi-Fujimoto disease alongside chronic bacterial lymphadenitis was made on the basis of her response to clindamycin, and the chronic course of her illness and subsequent persistence of the swelling managed on an outpatient basis. The case study describes the initial diagnostic considerations and management as well as a review of the disease pathology.
AB - The evaluation of pediatric neck masses offers the opportunity for consideration of a diverse range of pathologies, from infectious to neoplastic. A 16-year-old female presented with 2 weeks of worsening swelling and pain of a left-sided neck mass. Findings were consistent with Epstein–Barr virus and cytomegalovirus coinfection, but considering profound lymphadenopathy of the supraclavicular, mammillary, and axillary chains, further investigations were undertaken. Hematopathologic examination demonstrated necrotizing lymphadenitis, consistent with Kikuchi-Fujimoto disease. A diagnosis of Kikuchi-Fujimoto disease alongside chronic bacterial lymphadenitis was made on the basis of her response to clindamycin, and the chronic course of her illness and subsequent persistence of the swelling managed on an outpatient basis. The case study describes the initial diagnostic considerations and management as well as a review of the disease pathology.
KW - Hospital medicine
KW - Kikuchi-Fujimoto disease
KW - Pediatric neck mass
UR - http://www.scopus.com/inward/record.url?scp=85140331446&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85140331446&partnerID=8YFLogxK
U2 - 10.1177/2050313X20962640
DO - 10.1177/2050313X20962640
M3 - Article
AN - SCOPUS:85140331446
SN - 2050-313X
VL - 8
JO - SAGE Open Medical Case Reports
JF - SAGE Open Medical Case Reports
ER -