Evaluation of a new DNA test for detection of carcinogenic human papillomavirus

Philip E. Castle, Erin C. Gutierrez, Sharon V. Leitch, Courtney E. Maus, Ray A. McMillian, William A. Nussbaumer, Laurence M. Vaughan, Cosette M. Wheeler, Patti E. Gravitt, Mark Schiffman

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


Using archived specimens, we evaluated a new automated real-time PCR assay (BD Diagnostics) that detects all carcinogenic human papillomaviruses (HPV) and provides HPV genotyping for seven of them, including HPV16 and HPV18, the two most carcinogenic HPV genotypes. We found comparable results with Hybrid Capture 2 (HC2) for detection of carcinogenic HPV (n = 473) and with Linear Array and Line Blot Assay (n = 371) for detection of individual HPV genotypes.

Original languageEnglish (US)
Pages (from-to)3029-3032
Number of pages4
JournalJournal of Clinical Microbiology
Issue number8
StatePublished - Aug 2011
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology (medical)


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