Etiology of adolescent idiopathic scoliosis: A literature review

Sina Rashidi Kikanloo, Sandip Parshottam Tarpada, Woojin Cho

Research output: Contribution to journalArticlepeer-review

46 Scopus citations


Adolescent idiopathic scoliosis (AIS) is the peripubertal development of spinal curvature of a minimum of 10°. AIS is thought to be attributable to genetic factors, nutrition, early exposure to toxins, and hormonal dysregulation. Recent literature suggests these factors may compound to determine both disease onset and severity. Currently, treatment is limited to observation, bracing, and surgical intervention. Intervention is presently determined by severity and risk of curve progression. As they emerge, new therapies may target specific etiologies of AIS.

Original languageEnglish (US)
Pages (from-to)519-526
Number of pages8
JournalAsian Spine Journal
Issue number3
StatePublished - Jun 1 2019


  • Adolescent
  • Adolescent idiopathic scoliosis
  • Cobb angle
  • Etiology
  • Review
  • Scoliosis

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine


Dive into the research topics of 'Etiology of adolescent idiopathic scoliosis: A literature review'. Together they form a unique fingerprint.

Cite this