TY - JOUR
T1 - Estrogen Replacement Therapy in Breast Cancer Survivors
T2 - A Time for Change
AU - Cobleigh, Melody A.
AU - Berris, Robert F.
AU - Bush, Trudy
AU - Davidson, Nancy E.
AU - Robert, Nicholas J.
AU - Sparano, Joseph A.
AU - Tormey, Douglas C.
AU - Wood, William C.
PY - 1994/8
Y1 - 1994/8
N2 - POSTMENOPAUSAL women often experience annoying and sometimes debilitating menopausal symptoms, and breast cancer survivors are no exception. Hot flashes, dyspareunia, atrophic vaginitis with attendant urinary tract symptoms, sleep disturbance, and mood change are among these symptoms. Coronary artery disease and osteoporosis may be more insidious, but potentially fatal consequences of menopausal estrogen decline. Estrogen replacement therapy (ERT) has been shown to ameliorate these problems,1,2 and as informed consumers, breast cancer survivors are increasingly inquiring about and/or requesting ERT.3 There are more breast cancer survivors alive now than ever before, so their nononcologic health problems are a growing concern. A dramatic rise in the incidence rates of breast cancer occurred in the United States between 1982 and 1987, presumably because of increased screening.4 The incidence of noninvasive and of small, invasive, axillary nodenegative breast cancers rose concurrently.4 Five-year survival rates for breast cancer patients also have been.
AB - POSTMENOPAUSAL women often experience annoying and sometimes debilitating menopausal symptoms, and breast cancer survivors are no exception. Hot flashes, dyspareunia, atrophic vaginitis with attendant urinary tract symptoms, sleep disturbance, and mood change are among these symptoms. Coronary artery disease and osteoporosis may be more insidious, but potentially fatal consequences of menopausal estrogen decline. Estrogen replacement therapy (ERT) has been shown to ameliorate these problems,1,2 and as informed consumers, breast cancer survivors are increasingly inquiring about and/or requesting ERT.3 There are more breast cancer survivors alive now than ever before, so their nononcologic health problems are a growing concern. A dramatic rise in the incidence rates of breast cancer occurred in the United States between 1982 and 1987, presumably because of increased screening.4 The incidence of noninvasive and of small, invasive, axillary nodenegative breast cancers rose concurrently.4 Five-year survival rates for breast cancer patients also have been.
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U2 - 10.1001/jama.1994.03520070060039
DO - 10.1001/jama.1994.03520070060039
M3 - Article
C2 - 8046809
AN - SCOPUS:84942384277
SN - 0098-7484
VL - 272
SP - 540
EP - 545
JO - JAMA: The Journal of the American Medical Association
JF - JAMA: The Journal of the American Medical Association
IS - 7
ER -