Epidemiology, Pathogenesis, and Diagnosis of Cardiac Sarcoidosis

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations


Cardiac sarcoidosis (CS) is a widely underdiagnosed yet clinically significant form of granulomatous myocarditis associated with significant morbidity and mortality. Clinical presentation ranges from silent cardiac involvement detected on imaging to cardiomyopathy or sudden cardiac death. Diagnosis of CS remains challenging due to the lack of sensitivity and specificity of any single diagnostic method, underscoring the importance of elevated clinical suspicion and the use of multimodality imaging to guide diagnosis and treatment. In this review, we discuss the epidemiology, pathogenesis, clinical features, and diagnosis of this clinically evading and enigmatic disease.

Original languageEnglish (US)
Pages (from-to)78-93
Number of pages16
JournalMethodist DeBakey cardiovascular journal
Issue number2
StatePublished - 2022


  • cardiac FDG-PET
  • cardiac sarcoidosis
  • granulomatous myocarditis
  • inflammatory cardiomyopathy

ASJC Scopus subject areas

  • Medicine(all)


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