TY - JOUR
T1 - Endodermal sinus tumor and embryonal carcinoma of the ovary in a 53- year-old woman
AU - Kammerer-Doak, Dorothy
AU - Baurick, Karl
AU - Black, William
AU - Barbo, Dorothy M.
AU - Smith, Harriet O.
PY - 1996/10
Y1 - 1996/10
N2 - Background: Germ cell tumors, the most common ovarian malignancies in females under the age of 21, are rare in older women. We report an unusual case of a mixed embryonal carcinoma and endodermal sinus germ cell tumor in a perimenopausal patient and review the differential diagnosis and management of these malignancies with respect to age. Case: A 53-year-old woman complaining of irregular menses and pelvic pain was found to have a large pelvic mass and a positive pregnancy test. Subsequent investigation revealed a large left adnexal mass, and an elevated β-HCG and α-AFP. At laparotomy, a mixed germ cell tumor was found. The patient was treated with multiagent chemotherapy and currently is without evidence of disease. Conclusion: Although rare, the diagnosis of germ cell tumor should be considered in older women presenting with a large pelvic mass. The treatment and prognosis is similar regardless of age, except that reproductive-sparing surgery is not a priority in the older patient.
AB - Background: Germ cell tumors, the most common ovarian malignancies in females under the age of 21, are rare in older women. We report an unusual case of a mixed embryonal carcinoma and endodermal sinus germ cell tumor in a perimenopausal patient and review the differential diagnosis and management of these malignancies with respect to age. Case: A 53-year-old woman complaining of irregular menses and pelvic pain was found to have a large pelvic mass and a positive pregnancy test. Subsequent investigation revealed a large left adnexal mass, and an elevated β-HCG and α-AFP. At laparotomy, a mixed germ cell tumor was found. The patient was treated with multiagent chemotherapy and currently is without evidence of disease. Conclusion: Although rare, the diagnosis of germ cell tumor should be considered in older women presenting with a large pelvic mass. The treatment and prognosis is similar regardless of age, except that reproductive-sparing surgery is not a priority in the older patient.
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U2 - 10.1006/gyno.1996.0292
DO - 10.1006/gyno.1996.0292
M3 - Article
C2 - 8898183
AN - SCOPUS:0030272466
SN - 0090-8258
VL - 63
SP - 133
EP - 137
JO - Gynecologic Oncology
JF - Gynecologic Oncology
IS - 1
ER -