Endodermal sinus tumor and embryonal carcinoma of the ovary in a 53- year-old woman

Dorothy Kammerer-Doak, Karl Baurick, William Black, Dorothy M. Barbo, Harriet O. Smith

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


Background: Germ cell tumors, the most common ovarian malignancies in females under the age of 21, are rare in older women. We report an unusual case of a mixed embryonal carcinoma and endodermal sinus germ cell tumor in a perimenopausal patient and review the differential diagnosis and management of these malignancies with respect to age. Case: A 53-year-old woman complaining of irregular menses and pelvic pain was found to have a large pelvic mass and a positive pregnancy test. Subsequent investigation revealed a large left adnexal mass, and an elevated β-HCG and α-AFP. At laparotomy, a mixed germ cell tumor was found. The patient was treated with multiagent chemotherapy and currently is without evidence of disease. Conclusion: Although rare, the diagnosis of germ cell tumor should be considered in older women presenting with a large pelvic mass. The treatment and prognosis is similar regardless of age, except that reproductive-sparing surgery is not a priority in the older patient.

Original languageEnglish (US)
Pages (from-to)133-137
Number of pages5
JournalGynecologic Oncology
Issue number1
StatePublished - Oct 1996
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Obstetrics and Gynecology


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