Effect of lateral positioning on upper airway size and morphology in sedated children

Ronald S. Litman, Nicole Wake, Lai Ming Lisa Chan, Joseph M. McDonough, Sanghun Sin, Soroosh Mahboubi, Raanan Arens

Research output: Contribution to journalArticlepeer-review

71 Scopus citations


Background: Lateral positioning decreases upper airway obstruction in paralyzed, anesthetized adults and in individuals with sleep apnea during sleep. The authors hypothesized that lateral positioning increases upper airway cross-sectional area and total upper airway volume when compared with the supine position in sedated, spontaneously breathing children. Methods: Children aged 2-12 yr requiring magnetic resonance imaging examination of the head or neck region using deep sedation with propofol were studied. Exclusion criteria included any type of anatomical or neurologic entity that could influence upper airway shape or size. T1 axial scans of the upper airway were obtained in the supine and lateral positions, with the head and neck axes maintained neutral. Using software based on fuzzy connectedness segmentation (3D-VIEWNIX; Medical Imaging Processing Group, University of Pennsylvania, Philadelphia, PA), the magnetic resonance images were processed and segmented to render a three-dimensional reconstruction of the upper airway. Total airway volumes and cross-sectional areas were computed between the nasal vomer and the vocal cords. Two-way paired t tests were used to compare airway sizes between supine and lateral positions. Results: Sixteen of 17 children analyzed had increases in upper airway total volume. The total airway volume (mean ± SD) was 6.0 ± 2.9 ml3 in the supine position and 8.7 ± 2.5 ml 3 in the lateral position (P < 0.001). All noncartilaginous areas of the upper airway increased in area in the lateral compared with the supine position. The region between the tip of the epiglottis and vocal cords demonstrated the greatest relative percent change. Conclusions: The upper airway of a sedated, spontaneously breathing child widens in the lateral position. The region between the tip of the epiglottis and the vocal cords demonstrates the greatest relative percent increase in size.

Original languageEnglish (US)
Pages (from-to)484-488
Number of pages5
Issue number3
StatePublished - Sep 2005

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine


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