Doppler velocimetry and placental disease

Luis A. Bracero, Debra Beneck, Nancy Kirshenbaum, Marianne Peiffer, Patricia Stalter, Harold Schulman

Research output: Contribution to journalArticlepeer-review

85 Scopus citations


Quantitative placental examinations were performed on 47 women who had Doppler flow velocity studies of the umbilical artery during their pregnancy. The systolic-diastolic ratio of the umbilical artery was used as the measurement parameter to divide the study population into two groups. Group 1 consisted of women with normal systolic-diastolic ratios (systolic-diastolic <3), and group 2 consisted of women with an elevated systolic-diastolic ratio (systolic-diastolic ≥3). The group with an increase in systolic-diastolic ratio had more perinatal complications as demonstrated by two stillbirths, a higher incidence of cesarean deliveries for fetal distress, and more admissions to the neonatal intensive care unit. Significant differences were found when gestational age at delivery, placental weight, birth weight, and the number of small muscular arteries in the placenta were compared. Since gestational age may have accounted for the difference in placental findings, patients were matched for gestational age. The placental weights were comparable, but there were fewer small muscular arteries in those patients with an increase in systolic-diastolic ratio (p < 0.001). In acidition, when these findings were examined to determine the influence of diminished uterine flow velocity, none was found.

Original languageEnglish (US)
Pages (from-to)388-393
Number of pages6
JournalAmerican Journal of Obstetrics and Gynecology
Issue number2
StatePublished - Aug 1989


  • Doppler ultrasound
  • Umbilical artery velocity waveforms
  • placenta

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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