TY - JOUR
T1 - Distal embolization during lower extremity endovascular interventions
AU - Ochoa Chaar, Cassius I.
AU - Shebl, Fatma
AU - Sumpio, Bauer
AU - Dardik, Alan
AU - Indes, Jeffrey
AU - Sarac, Timur
N1 - Publisher Copyright:
© 2017 Society for Vascular Surgery
PY - 2017/7
Y1 - 2017/7
N2 - Objective Distal embolization (DE) during peripheral arterial endovascular interventions is a well-known complication that is poorly studied. The goal of this study was to determine the incidence, risk factors, and effect of DE on the outcomes of lower extremity endovascular interventions (LEIs). Methods All LEIs between 2010 and 2014 in the Vascular Study Group of New England (VSGNE) database were reviewed. Patient characteristics were analyzed to determine predictors of DE. LEIs involving the superficial femoral artery (SFA) were reviewed to assess the effect of type of treatment on DE. The outcomes examined were loss of patency, limb loss, and mortality after LEI involving the SFA. A multivariable regression was used to determine predictors of DE. Results There were 10,875 procedures. The incidence of DE was 17.3 per 1000 procedures, and 68% required treatment (57% endovascular, 11% open surgery). DE was more common in patients treated for critical limb ischemia compared with claudication (relative risk [RR], 2.06; 95% confidence interval [CI], 1.24-3.45; P =.006) and for emergency interventions compared with elective (RR, 2.98; 95% CI, 1.22-7.30; P =.017). DE increased with the number of arteries treated (P <.0001) and with the length of occlusion (P <.0001). The SFA was the most commonly treated artery (4751 [43.7%]). In comparison with atherectomy and balloon angioplasty, stenting alone (RR, 0.36; 95% CI, 0.17-0.73; P =.005), balloon angioplasty alone (RR, 0.23; 95% CI, 0.13-0.41; P <.0001), and combined stenting and balloon angioplasty (RR, 0.29; 95% CI, 0.17-0.49; P <.0001) were associated with a significantly lower risk of DE. DE was not significantly associated with loss of patency, major amputation, or mortality. Conclusions The incidence of DE during LEIs is 1% to 2% in the VSGNE database, and most patients are treated with additional endovascular interventions. The incidence increases in patients with critical limb ischemia and with the use of atherectomy.
AB - Objective Distal embolization (DE) during peripheral arterial endovascular interventions is a well-known complication that is poorly studied. The goal of this study was to determine the incidence, risk factors, and effect of DE on the outcomes of lower extremity endovascular interventions (LEIs). Methods All LEIs between 2010 and 2014 in the Vascular Study Group of New England (VSGNE) database were reviewed. Patient characteristics were analyzed to determine predictors of DE. LEIs involving the superficial femoral artery (SFA) were reviewed to assess the effect of type of treatment on DE. The outcomes examined were loss of patency, limb loss, and mortality after LEI involving the SFA. A multivariable regression was used to determine predictors of DE. Results There were 10,875 procedures. The incidence of DE was 17.3 per 1000 procedures, and 68% required treatment (57% endovascular, 11% open surgery). DE was more common in patients treated for critical limb ischemia compared with claudication (relative risk [RR], 2.06; 95% confidence interval [CI], 1.24-3.45; P =.006) and for emergency interventions compared with elective (RR, 2.98; 95% CI, 1.22-7.30; P =.017). DE increased with the number of arteries treated (P <.0001) and with the length of occlusion (P <.0001). The SFA was the most commonly treated artery (4751 [43.7%]). In comparison with atherectomy and balloon angioplasty, stenting alone (RR, 0.36; 95% CI, 0.17-0.73; P =.005), balloon angioplasty alone (RR, 0.23; 95% CI, 0.13-0.41; P <.0001), and combined stenting and balloon angioplasty (RR, 0.29; 95% CI, 0.17-0.49; P <.0001) were associated with a significantly lower risk of DE. DE was not significantly associated with loss of patency, major amputation, or mortality. Conclusions The incidence of DE during LEIs is 1% to 2% in the VSGNE database, and most patients are treated with additional endovascular interventions. The incidence increases in patients with critical limb ischemia and with the use of atherectomy.
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U2 - 10.1016/j.jvs.2017.01.032
DO - 10.1016/j.jvs.2017.01.032
M3 - Article
C2 - 28366300
AN - SCOPUS:85016483388
SN - 0741-5214
VL - 66
SP - 143
EP - 150
JO - Journal of Vascular Surgery
JF - Journal of Vascular Surgery
IS - 1
ER -