Abstract
Autoimmune phenomena are common in patients with chronic hepatitis C. Management of chronic hepatitis C/autoimmune hepatitis syndrome has until recently been problematic due to the adverse effects of interferon on autoimmune processes and immunosuppression on viral replication. In this report we describe 3 patients with chronic hepatitis C/autoimmune hepatitis overlap syndrome who responded rapidly to direct acting antiviral therapy. The resolution of the autoimmune process supports a direct viral role in its pathophysiology.
Original language | English (US) |
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Pages (from-to) | 632-636 |
Number of pages | 5 |
Journal | World Journal of Hepatology |
Volume | 8 |
Issue number | 14 |
DOIs | |
State | Published - May 18 2016 |
Keywords
- Autoimmune hepatitis
- Direct acting antiviral therapy
- Hepatitis C
- Overlap syndrome
ASJC Scopus subject areas
- Hepatology