Diagnostic clues and more from photographs

Asao Hirano, Reika Wate

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations


During over 50 years of the first author's career in neuropathology at Montefiore Medical Center in New York, we have come across certain interesting neuropathological findings. In this communication, some photographs showing macroscopic, microscopic and electron microscopic significant findings are selected to illustrate usefulness not only for the diagnosis but also for understanding of the nervous system. The six topics presented in this paper are: (i) unattached presynaptic terminals in cerebellar neuroblastoma; (ii) neurofibrillary tangle formation in the nucleus basalis of Meynert ipsilateral to a massive cerebral infarct; (iii) orderly arrangement of tumor cells in leptomeningeal carcinomatosis; (iv) interface between craniopharyngioma and brain tissue; (v) neurofibrillary tangles and Lewy bodies in a single neuron; and (vi) Cu/Zn superoxide dismutase positive Lewy body-like hyaline inclusions in anterior horn cells in familial motor neuron diseases. Analyses of these findings are presented for an educational purpose.

Original languageEnglish (US)
Pages (from-to)1-9
Number of pages9
Issue number1
StatePublished - Feb 2007


  • Craniopharyngioma
  • Leptomeningeal carcinomatosis
  • Lewy body-like inclusions
  • Neuroblastoma
  • Neurofibrillary tangles

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Clinical Neurology


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