Desipramine for the treatment of "pure" dysthymia versus "double" depression

Deborah B. Marin, James H. Kocsis, Allen J. Frances, Michael Parides

Research output: Contribution to journalArticlepeer-review

41 Scopus citations


The authors report results of an 8-week, open trial of desipramine in 42 patients with DSM-III-R dysthymia with a concurrent diagnosis of major depression ("double" depression) and 33 patients with dysthymia who had no other depressive diagnosis ("pure" dysthymia). Either complete or partial remission was achieved by 70% of the patients with "pure" dysthymia. This compared favorably with but was not significantly different from results in the "double" depression group.

Original languageEnglish (US)
Pages (from-to)1079-1080
Number of pages2
JournalAmerican Journal of Psychiatry
Issue number7
StatePublished - Jul 1994
Externally publishedYes

ASJC Scopus subject areas

  • Psychiatry and Mental health


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