Cysteine-activated hydrogen sulfide (H2S) donors

Yu Zhao; Hua Wang; Ming Xian

doi:10.1021/ja1085723

Cysteine-activated hydrogen sulfide (H₂S) donors

Yu Zhao, Hua Wang, Ming Xian

Research output: Contribution to journal › Article › peer-review

201 Scopus citations

Abstract

H₂S, the newly discovered gasotransmitter, plays important roles in biological systems. However, the research on H₂S has been hindered by the lack of controllable H₂S donors that could mimic the slow and continuous H₂S generation process in vivo. Herein we report a series of cysteine-activated H₂S donors. Structural modifications of these molecules can regulate the rates of H₂S generation. These compounds can be useful tools in H₂S research.

Original language	English (US)
Pages (from-to)	15-17
Number of pages	3
Journal	Journal of the American Chemical Society
Volume	133
Issue number	1
DOIs	https://doi.org/10.1021/ja1085723
State	Published - Jan 12 2011
Externally published	Yes

ASJC Scopus subject areas

Catalysis
Chemistry(all)
Biochemistry
Colloid and Surface Chemistry

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10.1021/ja1085723

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Cysteine-activated hydrogen sulfide (H₂S) donors

Abstract

ASJC Scopus subject areas

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