Cysteine-activated hydrogen sulfide (H2S) donors

Yu Zhao, Hua Wang, Ming Xian

Research output: Contribution to journalArticlepeer-review

201 Scopus citations


H2S, the newly discovered gasotransmitter, plays important roles in biological systems. However, the research on H2S has been hindered by the lack of controllable H2S donors that could mimic the slow and continuous H2S generation process in vivo. Herein we report a series of cysteine-activated H2S donors. Structural modifications of these molecules can regulate the rates of H2S generation. These compounds can be useful tools in H2S research.

Original languageEnglish (US)
Pages (from-to)15-17
Number of pages3
JournalJournal of the American Chemical Society
Issue number1
StatePublished - Jan 12 2011
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry


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